Protein Alignment Ance-3 and Ace

DIOPT Version :9

• Sequence 1: NP_001033904.1
• Gene: Ance-3 / 34808
• FlyBaseID: FBgn0032536
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_997507.1
• Gene: Ace / 11421
• MGIID: 87874
• Length: 1312
• Species: Mus musculus
• Alignment Length: 669
• Identity: 254/669 - (37%)
• Similarity: 372/669 - (55%)
• Gaps: 77/669 - (11%)

  Fly   152 FNPNDQY-NYNNNPNVEFVGINNRNRFENPFLSNQDRFNLNQGY-----LERQRYQQDRRYQQEL 210
            |.|..|: ...|..|.|.:|          :..||.|..|...|     ||....:.||..::..
Mouse   608 FQPVSQWLEEQNQRNGEVLG----------WPENQWRPPLPDNYPEGIDLETDEAKADRFVEEYD 662

  Fly   211 EKLRILLVESDQKGSLECTANVAAQWNFETNVNDFTQTEALNAQQRYVEFQRITAEQSKRINKDL 275
            ...::||.|..:           |.|.:.||:.              :|..:|..|:|..::...
Mouse   663 RTAQVLLNEYAE-----------ANWQYNTNIT--------------IEGSKILLEKSTEVSNHT 702

  Fly   276 I--------FD---------RRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEICAY 323
            :        ||         :|:.::|   ..:....||...|:.||::|.:|...|:.:.||..
Mouse   703 LKYGTRAKTFDVSNFQNSSIKRIIKKL---QNLDRAVLPPKELEEYNQILLDMETTYSLSNICYT 764

  Fly   324 Q---QPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNV 385
            .   .|.:      |.|.::||.||.::||...|..:..|.||.:...:.:.::...::|.:|..
Mouse   765 NGTCMPLE------PDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGY 823

  Fly   386 TNGGEYWYLAYESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNM 450
            |:.|:.|...|||.|..||::.::::::|||..|||||||.|..:||.:.||...|||:|:||||
Mouse   824 TDAGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNM 888

  Fly   451 YGQSWSNVLDILIPYPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQ 515
            :.|:|||:.|::.|:|....||.|..|::||:||:.:|:.|:.||||:.:..|.|||:..|:.|:
Mouse   889 WAQTWSNIYDLVAPFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEK 953

  Fly   516 PLD-RRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPA 579
            |.| |.|:|.||||||.|..|||:|.||.:|...|:..||||.|||||:||:.||..||.||||.
Mouse   954 PTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPG 1018

  Fly   580 FHQAVGDAIGLSVSTPRHLQTLGLLQRSLDESSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFS 644
            ||:|:||.:.||||||:||.:|.||........||||:|..||:||:||:||:..:|.||:.||.
Mouse  1019 FHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFD 1083

  Fly   645 GNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLC 709
            |:..|...|..:|:||.||.|:.|||.||:.|||||:|:|:|||:||::||.|.::|||.:..||
Mouse  1084 GSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALC 1148

  Fly   710 RESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFA 774
            |.:|.      ..|||:||||:...||.:|...|..|.|:||.|.::....:..:..:|:..||.
Mouse  1149 RAAGH------TGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFK 1207

  Fly   775 PLEEWLRQENLRTNEYVGW 793
            ||.|||..||.|..|.:||
Mouse  1208 PLTEWLVTENRRHGETLGW 1226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:188999	232/588 (39%)
Ace	NP_997507.1	Peptidase M2 1	35..635		9/36 (25%)
		Peptidase_M2	45..628	CDD:279709	7/29 (24%)
		Peptidase M2 2	636..1237		244/631 (39%)
		Peptidase_M2	649..1226	CDD:279709	238/616 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101615
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.770