Protein Alignment Ance-2 and Ace3

DIOPT Version :9

• Sequence 1: NP_788042.1
• Gene: Ance-2 / 34806
• FlyBaseID: FBgn0032535
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_006533116.1
• Gene: Ace3 / 217246
• MGIID: 3644400
• Length: 774
• Species: Mus musculus
• Alignment Length: 650
• Identity: 173/650 - (26%)
• Similarity: 284/650 - (43%)
• Gaps: 73/650 - (11%)

  Fly     7 LLLVGLTQAGSQP------DATLERFLNETNQQLAVIYDQAVLAQLLNE-LRGPNDLVA------ 58
            ||||.|:.....|      :.:|..|.:|...:|.:.:.:.....:||| :....:.|.
Mouse    25 LLLVLLSHRQLLPWLRTVGETSLNDFYSEAQAKLFLQFYEQTAQVVLNEFMEATWNYVTNITKQN 89

  Fly    59 ---LLEIEVTDDKLVKYVRTLTTRKAKFKRLGLGDSRQRRLLDKIPQLGYEALSGRDL------- 113
               :|:.|....:.:.|   .:||...|:.....:...:|:|.|:..:...||...||
Mouse    90 QKNMLQKEADRSQFMLY---FSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALPTEDLLEVTDRG 151

  Fly   114 ------------KLVYALASSMSDNYHNVKLCAYKQPGNCTLRLIPEVQSIVQGSRDLDEIEYYW 166
                        :....|.:.|...|:..::|.  ..|.| |.|.|::|.|:..|||..|:.:.|
Mouse   152 PGRPGTHTPAPERRYNRLLTYMETAYNRAEVCL--DEGPC-LTLEPDLQEIMATSRDQKELLWAW 213

  Fly   167 FEWRSRTGLATRSQFVDFMDLYKKTAQLNGYPRAEDYWFRSLELKGQETMNL-LDRIMHGLRPLF 230
            ..||...|...|..|.|::.|..|.||.|||......|....|   .:|:.. |:::...|:||:
Mouse   214 QGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGALWRSKYE---SDTLEEDLEQLYKELQPLY 275

  Fly   231 LQFHAHVRGSLRKMHGEHLVPRNRPYPQHLAEVFIGNAFRRVEAEW--YVD--LPSPEIGLANIT 291
            |..||:||.||.:.:|..|:....|.|.||    :||.:.:   .|  .:|  ||.|.....:||
Mouse   276 LNLHAYVRRSLYRYYGPELIDLRGPIPAHL----LGNMWAQ---SWNNILDLVLPYPTKAPEDIT 333

  Fly   292 QEL---HRRGLSTTQRVFWNVAEYFRALGFPQLENSLW--TYAQKVSSDDDDRCWHKAWRYYALP 351
            ..:   |.|    .:::|.....:|.::|......:.|  :..:|.:...:..|...:|.:|...
Mouse   334 AIMKIQHWR----PEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFN 394

  Fly   352 RTNFTYCPLNDEERFFNMFEAQSDLQYYRAASIQPTLLQEEPFPNFSDAIGKCFSMAASSPRFLR 416
            ......|.....|...::|.....:||:........:.||...|.|.:|:|...:::.||.::|.
Mouse   395 DFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLL 459

  Fly   417 KLGMLRDNKWKELPARLNRLYIQGLRVVFLLPVFYVLDRYRVEVLAGHI-KADDNEAYWRLTELY 480
            ..|:| ....::....:|.|....|..:..:|..|::|::|.::..|.| |...|:.:|.....|
Mouse   460 ARGLL-SQPHQDSEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKY 523

  Fly   481 TGAAAPTKRTNEQFDVPAKLLMEVDDQYASNFLSIVLQFQLLKHFCTITGQFEMGNPRKPLDMCD 545
            .|...|..|:::.||..||..:..:..|...||.::|||||.:..|..:|  .:|    ||..||
Mouse   524 QGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASG--HVG----PLHQCD 582

  Fly   546 LSDQRGIGEILKRAMSLGSSVHYREVLKVLLGEPEISIDGLLTYFQPLQDWLQHQNQENNLEVGW 610
            ..:.:..|:||...:.||||..:||||:.:.||..||....||||:||.|||..:|.:....:||
Mouse   583 NYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGW 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-2	NP_788042.1	GluZincin	26..601	CDD:301352	163/614 (27%)
Ace3	XP_006533116.1	Peptidase_M2	51..647	CDD:366618	163/622 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266227at33208
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920