Protein Alignment Ance and Ace3

DIOPT Version :9

• Sequence 1: NP_001285915.1
• Gene: Ance / 34805
• FlyBaseID: FBgn0012037
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001245166.1
• Gene: Ace3 / 498012
• RGDID: 1561299
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 233/585 - (39%)
• Similarity: 352/585 - (60%)
• Gaps: 9/585 - (1%)

  Fly    22 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWR 86
            |.|||.:|:...:......|...||.|.|.:|||.:|::...:...|.::||....:....|:..
  Rat    35 EAQAKMFLQFYEQTARVVLNELMEATWNYVTNITKQNQENMLQKEVERSQFMLYFGTRARMFRID 99

  Fly    87 SYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEE 151
            .:|..|:||:...|..:..:|||.:|:.|....|:.|::.:.:.:||  .|...| :.|:|::||
  Rat   100 HFQDLDVKRRLSKLRNIDKSALPVEDFQEFNRLLTYMKTAYGRAEVC--LDEGPC-MPLEPDLEE 161

  Fly   152 VISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLDEYEDDTFEQQ 216
            :::.|||.:||.:.|:.:.|..|..:|..||.||.|:.|||:.|.:......|..:||.||.|:.
  Rat   162 IMATSRDQKELLWAWQGWRDAIGRQLRPVFEDYVHLSNKAAQYNGYKDMGALWRSKYESDTLEED 226

  Fly   217 LEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKP 281
            ||.::.:::|||..:|.|||..|.::||..::...||||.|||||||||.|:.|.|:|.|:|.||
  Rat   227 LEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPNKP 291

  Fly   282 LVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLT 346
            ..|::..|:.|.:.|.|||:..:.|||||.:...|..||.||::|||.|||::.||.|:|:||..
  Rat   292 PEDITKIMKNQHWRPEKMFEEANLFFTSMGMLPAPPAFWMKSMMEKPVDGREVECHTSSWNFYRL 356

  Fly   347 DDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHL 411
            :|.|:|:||.||...|.::.|::|||||:||.|:...:|:.||:|.|.||||..::||..:.|:|
  Rat   357 NDFRVKKCTEVTIGDLLSIFHQMGHIQYYLQCQNLSIIYQEGASPAFEEAVGSTITLSAFSHKYL 421

  Fly   412 EKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEY 476
            ...|||....:|.|..:|.|...||:||.|:||.:.:|.:||.:|.|.:.|..:|..:|.||.:|
  Rat   422 LTRGLLSQQHQDSEEEVNFLLSIALEKIAFIPFGYMIDLFRWKVFDGTIQKNAYNQEWWSLRLKY 486

  Fly   477 SGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCD 541
            .|:.|||.|||.|||..||:||.|::.|:||.:|.::|||.::..|..:|...      ||..||
  Rat   487 QGLCPPVPRSEDDFDPGAKFHIPANMPYIRYFLSLVLQFQLHEVLCRASGHVG------PLHRCD 545

  Fly   542 IYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGW 606
            ||.|..||....:.|.:|:|:||.:.|:...|:..:|.||:..||:||..||..||:|....:||
  Rat   546 IYNSKVAGKILGDFLKVGSSRPWQEVLKEITGKPNISTKALLTYFKPLLNWLVTENVKQGDILGW 610

  Fly   607  606
              Rat   611  610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance	NP_001285915.1	Peptidase_M2	19..606	CDD:279709	231/583 (40%)
Ace3	NP_001245166.1	Peptidase_M2	34..610	CDD:279709	231/583 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339578
Domainoid	1	1.000	532	1.000	Domainoid score	I271
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80337
Inparanoid	1	1.050	478	1.000	Inparanoid score	I1420
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266227at33208
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		mtm8935
orthoMCL	1	0.900	-	-		OOG6_101615
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.900