Protein Alignment Ance and ace2

DIOPT Version :10

• Sequence 1: NP_477046.1
• Gene: Ance / 34805
• FlyBaseID: FBgn0012037
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001007298.2
• Gene: ace2 / 492331
• ZFINID: ZDB-GENE-041114-6
• Length: 818
• Species: Danio rerio
• Alignment Length: 619
• Identity: 222/619 - (35%)
• Similarity: 352/619 - (56%)
• Gaps: 23/619 - (3%)

  Fly     2 RLFLLALLATLAVTQALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEIS 66
            |..||..||::|..|.:   |.:|:|:|...::|.:......|.|:|||.::|:.||..|:.|..
Zfish     4 RWLLLLALASVACCQTV---EDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENADKEAEAY 65

  Fly    67 AELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVK 131
            |..:::..:::.::..:.........:|.|.:.|...|..||..|..:||.:.:|.|.:.:....
Zfish    66 AIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTAT 130

  Fly   132 VCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNN 196
            ||...|.|.|. .|:|.:|.::::|||::|..:.|..:....|..:|..:|:||:|..:||||||
Zfish   131 VCKIDDPTDCQ-TLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNN 194

  Fly   197 FTSGAEAWLDEYE--DD-----TFEQQLED---IFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 251
            :....:.|..:||  ||     :.:|.:||   |:.:|.|||:::|.|||.:|:..|...:.|:
Zfish   195 YEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSD- 258

  Fly   252 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLP 316
            ..:|.||||:||.:.|:.:..::.|:|::|.:|||:.|.:||:..:::|:..:.||.|:|:..:.
Zfish   259 ACLPAHLLGDMWGRFWTNLYPLMIPYPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMF 323

  Fly   317 QDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQ 381
            .:||:.|:..||.: ||:|||.:|||.....|.|||.||:|..|...|||||:||.||.:.|::.
Zfish   324 DNFWNNSMFIKPEE-RDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNH 387

  Fly   382 PFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLL-KDYVRDDEARINQLFLTALDKIVFLPFA 445
            |::.|.|||.|||||||:::|||.:||.||:.:||| .|:.:|.|..||.|...||..:..|||.
Zfish   388 PYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFT 452

  Fly   446 FTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVS 510
            :.::::||.:|:.::.|..|...:|:::.|..|:...|.|.|...|.||.:|:|.|..::||...
Zfish   453 YMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTR 517

  Fly   511 FIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGER 575
            .|.||||.::.|..||...      ||..|||..|..||....:||.:|.|..|..|||...|..
Zfish   518 TIYQFQFQEALCKAAGHTG------PLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTT 576

  Fly   576 IMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTS 609
            .|..:.:..||..|..||:.||.|||...||..:
Zfish   577 KMDSQPLLHYFSTLMEWLKEENQKNNRVPGWNVN 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance	NP_477046.1	Peptidase_M2	19..606	CDD:460196	213/597 (36%)
ace2	NP_001007298.2	None