Protein Alignment Ance and Ance-2

DIOPT Version :9

• Sequence 1: NP_001285915.1
• Gene: Ance / 34805
• FlyBaseID: FBgn0012037
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_788042.1
• Gene: Ance-2 / 34806
• FlyBaseID: FBgn0032535
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 180/632 - (28%)
• Similarity: 313/632 - (49%)
• Gaps: 48/632 - (7%)

  Fly     3 LFLLALLATLAVTQALVKEEIQAKEYLENLNKELAKRTNVETEAAWAY------GSN-------- 53
            :::.|:|..:.:|||..:.:...:.:|...|::||.   :..:|..|.      |.|
  Fly     1 MWIFAVLLLVGLTQAGSQPDATLERFLNETNQQLAV---IYDQAVLAQLLNELRGPNDLVALLEI 62

  Fly    54 -ITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELL 117
             :||:          :|.|:::.:.:...||:.........:|....:.:|||.||...|...:.
  Fly    63 EVTDD----------KLVKYVRTLTTRKAKFKRLGLGDSRQRRLLDKIPQLGYEALSGRDLKLVY 117

  Fly   118 DTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFE 182
            ...|:|..|:..||:|.||....|.|.|.||::.::..|||.:|:.|||.|:..:.|.|.||||.
  Fly   118 ALASSMSDNYHNVKLCAYKQPGNCTLRLIPEVQSIVQGSRDLDEIEYYWFEWRSRTGLATRSQFV 182

  Fly   183 RYVELNTKAAKLNNFTSGAEAWLDEYE---DDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYG 244
            .:::|..|.|:||.:....:.|....|   .:|. ..|:.|...:|||:.|.|.:||..|||.:|
  Fly   183 DFMDLYKKTAQLNGYPRAEDYWFRSLELKGQETM-NLLDRIMHGLRPLFLQFHAHVRGSLRKMHG 246

  Fly   245 DAVVSETGPIPMHL----LGNMWAQ---QWSEIADIVSPFPEKPLVDVSAEMEKQGY-TPLKMFQ 301
            :.:|....|.|.||    :||.:.:   :|  ..|:  |.||..|.:::.|:.::|. |..::|.
  Fly   247 EHLVPRNRPYPQHLAEVFIGNAFRRVEAEW--YVDL--PSPEIGLANITQELHRRGLSTTQRVFW 307

  Fly   302 MGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVH 366
            ...::|.::...:|....|  :..:|.:...|..|...||.:|.........|....:::.|.:.
  Fly   308 NVAEYFRALGFPQLENSLW--TYAQKVSSDDDDRCWHKAWRYYALPRTNFTYCPLNDEERFFNMF 370

  Fly   367 HELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYV-RDDEARINQ 430
            .....:||:.....||.:.:....|.|.:|:|...|::.|:|:.|.|:|:|:|.. ::..||:|:
  Fly   371 EAQSDLQYYRAASIQPTLLQEEPFPNFSDAIGKCFSMAASSPRFLRKLGMLRDNKWKELPARLNR 435

  Fly   431 LFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAK 495
            |::..|..:..||..:.:|:||..:..|.: ||:.|.|:|:|.:.|:|...|..|:.:.||.|||
  Fly   436 LYIQGLRVVFLLPVFYVLDRYRVEVLAGHI-KADDNEAYWRLTELYTGAAAPTKRTNEQFDVPAK 499

  Fly   496 YHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGA 560
            ..:..|.:|....:|.::|||..|..|...||::..|...|||.||:......|......:|:|:
  Fly   500 LLMEVDDQYASNFLSIVLQFQLLKHFCTITGQFEMGNPRKPLDMCDLSDQRGIGEILKRAMSLGS 564

  Fly   561 SKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWT 607
            |..:.:.|:...||..:|...:..||:||:.||:.:|.:||:.:|||
  Fly   565 SVHYREVLKVLLGEPEISIDGLLTYFQPLQDWLQHQNQENNLEVGWT 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance	NP_001285915.1	Peptidase_M2	19..606	CDD:279709	172/613 (28%)
Ance-2	NP_788042.1	GluZincin	26..601	CDD:301352	169/595 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5260
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16282at33392
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870