Protein Alignment Ance and acn-1

DIOPT Version :9

• Sequence 1: NP_001285915.1
• Gene: Ance / 34805
• FlyBaseID: FBgn0012037
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001024453.1
• Gene: acn-1 / 180780
• WormBaseID: WBGene00000039
• Length: 906
• Species: Caenorhabditis elegans
• Alignment Length: 618
• Identity: 158/618 - (25%)
• Similarity: 277/618 - (44%)
• Gaps: 58/618 - (9%)

  Fly    19 VKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKF 83
            :|:|.:.:.:|.....|..|.......:.|.|.::.:...:...:|....|..|::..:....:|
 Worm   175 IKDEEKLRSWLAGYEAEAIKVLREVALSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQF 239

  Fly    84 QWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDP- 147
            ...|...|.:.||...::..|.:||....:|:.....:|:..        |.||||.||..:.|
 Worm   240 DMASVTDEKVMRQLGYVSFEGMSALAPSRFADYSQAQAALNR--------DSKDSTICDKDVPPP 296

  Fly   148 ------EIEEVISKSRDHEELAYYWREFYDKAGTAV---RSQFERYVELNTKAAKLNNFTSGAEA 203
                  :::.:....:|...|.:.|..:.    ||:   :..:...:.::.:.||||.|.:|...
 Worm   297 CALQKIDMDSIFRNEKDASRLQHLWVSYV----TAIAKSKPSYNNIITISNEGAKLNGFANGGAM 357

  Fly   204 WLDEYE--------DDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAV-VSETGPIPMHLL 259
            |...::        :....:|::.|::.|:|.||.:|.|:|.:|...|.:.| :|:.||||.||.
 Worm   358 WRSAFDMSSKVHKAEFDLNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLF 422

  Fly   260 GNMWAQQWSEIADIVSPFPEK---PLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWD 321
            |::....||...:...||.|:   |...:|| ...|.||..|||.....:|.|.....||:.:|.
 Worm   423 GSLDGGDWSAHYEQTKPFEEESETPEAMLSA-FNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWT 486

  Fly   322 KSIIEKPTDGRDLVCH-ASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVY 385
            .||..: ...:|::|| |:|.|....:|.|:|.|.::.:......|..|....|...|:.|..::
 Worm   487 SSIFAR-VWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLF 550

  Fly   386 RTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRD--DEARINQLFLTALDKIVFLPFAFTM 448
            |..|:|...:|:.:..:...:.|.:|....|:.....|  |...||:|:..:|:....|||....
 Worm   551 REQASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFTIAA 615

  Fly   449 DKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDA-----PAKYHISADVEYLRYL 508
            |.:|:.||.|.|.|...|..:|::|::|.|:..|...:..:.||     .::.|..|    .|.|
 Worm   616 DNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPA----TRTL 676

  Fly   509 VSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNG 573
            :|::::||..|:.|       |:...|. :.|.:  |..........:.:|:|..|..|||..:|
 Worm   677 ISYVLKFQILKALC-------PEGTILS-EGCIL--SEDTTEKLRETMKLGSSITWLKALEMISG 731

  Fly   574 ERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGW 606
            :..:..:.:.||:|||..||...|..:.|.:||
 Worm   732 KGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance	NP_001285915.1	Peptidase_M2	19..606	CDD:279709	156/616 (25%)
acn-1	NP_001024453.1	Peptidase_M2	175..764	CDD:279709	156/616 (25%)
		EB	<794..833	CDD:279949

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I1460
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2232
Isobase	1	0.950	-	0	Normalized mean entropy	S5260
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	1	0.900	-	-		OOG6_101615
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2384
SonicParanoid	1	1.000	-	-		X1436
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.940