Protein Alignment Ance and ace2

DIOPT Version :10

• Sequence 1: NP_477046.1
• Gene: Ance / 34805
• FlyBaseID: FBgn0012037
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_002938293.2
• Gene: ace2 / 100486137
• XenbaseID: XB-GENE-487117
• Length: 862
• Species: Xenopus tropicalis
• Alignment Length: 618
• Identity: 227/618 - (36%)
• Similarity: 353/618 - (57%)
• Gaps: 22/618 - (3%)

  Fly     3 LFLLALLATLAVTQALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISA 67
            ||.:.||.....:|::..   ||:::|:...:|.....:....|.|.|.:||||||.:|.:|..|
 Frog     7 LFCIGLLLATGRSQSVTD---QARDFLKRFEQEAEVLYHQSALAQWEYNTNITDENAQKMSEAGA 68

  Fly    68 ELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKV 132
            :.:.|....:.::..|.........::.|...|::.|.|.||.:.|..|...|:.|.:.::...|
 Frog    69 KWSAFYTNASKNSEAFNKDYITDPSIELQLIFLSEKGSAILPAEKYTRLNQVLNEMSTIYSTHAV 133

  Fly   133 CDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNF 197
            |....|.:| |.|:|.:::::::|.|:||..:.|..:...||..:||.:|.||:|..:||:||.:
 Frog   134 CKPDGSKEC-LPLEPGLDKIMAESIDYEERLWAWEGWRAGAGKKMRSLYEEYVDLENEAARLNGY 197

  Fly   198 TSGAEAWLDEYE---DDTFEQQLEDIFADIR-------PLYQQIHGYVRFRLRKHYGDAVVSETG 252
            ....:.|...||   .|.:....:|:..|:.       |||:::|.:||..|::.||...:|::|
 Frog   198 NDYGDYWRGNYETLATDMYAYSRDDLIKDVERTYQEILPLYKELHAFVRGNLQQVYGSRYISDSG 262

  Fly   253 PIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQ 317
            .:|.||||:||.:.|:.:..::.|:|.|..:||:..|..||:|..:||:..:.||.|::|..|.:
 Frog   263 CLPAHLLGDMWGRFWTNLYPLMVPYPNKESIDVTPTMVAQGWTIERMFKEAEIFFKSVDLFALNE 327

  Fly   318 DFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQP 382
            :||:.|::|:|.|||.:|||.:|||..: :|.|||.||:|..:...|||||||||||.:.|..||
 Frog   328 NFWNNSMLEEPKDGRQVVCHPTAWDLGM-NDFRIKMCTKVNMEDFLTVHHELGHIQYDMAYAKQP 391

  Fly   383 FVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLL-KDYVRDDEARINQLFLTALDKIVFLPFAF 446
            |:.|.|||.|||||||:::|||.:|||||:.:.|| .::|.|.|..||.||..||..:..|||.:
 Frog   392 FMLRDGANEGFHEAVGEIMSLSAATPKHLKHLKLLDANFVEDQETEINFLFRQALAIVGTLPFTY 456

  Fly   447 TMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSF 511
            .::::||.:||||:.|..|...:|:::.|..|:..||...|...|.||.:|:|.|..::||....
 Frog   457 MLEQWRWKVFRGEIPKDQWMKTWWQMKRELVGVVEPVPHDETYCDPPALFHVSNDYSFIRYYTRT 521

  Fly   512 IIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERI 576
            |.||||..:.|..||...      ||..|||..|..|||....||.:|.:|.|.:||::..|...
 Frog   522 IYQFQFQDALCKAAGHVG------PLHTCDITNSKEAGAKLRAMLELGKAKSWTEALQSITGGVK 580

  Fly   577 MSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTS 609
            |..:.:.:|||||.|||:..|.:|.....|.|:
 Frog   581 MDSQPLLKYFEPLFVWLQKNNEENRRQSTWNTA 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance	NP_477046.1	Peptidase_M2	19..606	CDD:460196	220/597 (37%)
ace2	XP_002938293.2	Peptidase_M2	23..610	CDD:460196	220/597 (37%)
		Collectrin	622..772	CDD:465322