| Sequence 1: | NP_001285914.1 | Gene: | Smg5 / 34804 | FlyBaseID: | FBgn0019890 | Length: | 1177 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056142.2 | Gene: | SMG5 / 23381 | HGNCID: | 24644 | Length: | 1016 | Species: | Homo sapiens |
| Alignment Length: | 1246 | Identity: | 283/1246 - (22%) |
|---|---|---|---|
| Similarity: | 460/1246 - (36%) | Gaps: | 368/1246 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 43 KDLYRSLYTASKQLDDAKRNVQSVGQLFQHEIEEKRSLLVQLCKQIIFKDYQSVGKKVREVMWRR 107
Fly 108 GYYEFIAFVKKNWHKQCQDAATAQENMQKLERFLCAGIFNYKRLSARMEEIYDLDLKYLIDFSII 172
Fly 173 SDGYISDMIGDTMESSHSGTHAVDKSLEAVSFALDTIHSSLLSLGDLHRYFLDFR-IDSKLSISK 236
Fly 237 EQVAKYYLEAFKLNPAIGMAQNQLGTLHYGQNHDLDSTYHYLYSLVCIIPFELSENNLNKLF--- 298
Fly 299 AKHTEYLERMDPEKLD------FNIEDFFARFYLIVDIF-----FFDKEVPDFNALCHCVLIDLR 352
Fly 353 KILC---------------------SQQLRVPEPSIFKIVSILFFCLSKLKMINSPKVYSLHAFL 396
Fly 397 VAACSDLMDACIVSIEQTILARAQDNERFQAEYEERFQEFDTVVRKSRNEYKNWLAAVGECERKD 461
Fly 462 KKLMPRPHSLKDCSSDSRDSQHSGEEAKTQEAADGD------KIGEAVSTRSSDEAKESDLKTPL 520
Fly 521 SCKSKRRGMRLRRRRRKIAQSDDSSCYDSESELDTDFYSDEEDYTDLSSNFDTDFS-DIDAADPG 584
Fly 585 EPCGEERYAAANYSKKERKAGGGGGGGVGGVVYSDNEDVVIEEEKIVYPNEVERRSNSQEADSEE 649
Fly 650 LLRSFEVLQLNFKS-AEDAQSKPVAPPPVSFSEPPKKLVYRNKYTK-----------------IN 696
Fly 697 PNIVID---CLH----------------------------NEPTIR-------------ALKMLF 717
Fly 718 DWLRINPEILIGCYHSNPEFVHKIMKLLNYCNIDIFTRKVYFERDLLTTANVRDSL--VELFDVR 780
Fly 781 ANVPLTEDFAFKNFDIFQSTQITLDWETIIRERVTPQEESILRIFKMVDFGFFICKQKKFNYRFC 845
Fly 846 VKTRRFTETQKKKQREEKKGGGSRRRERRTAPKTNRTKRNEGRTRRYSDRKNGIVRKSYTSNEEK 910
Fly 911 DTVEECRKMPRKGYLRNRNAEKAAAVITSATGTSVAGGTSASTTTNSVIEKLNLQSSSGADEERS 975
Fly 976 EAKSKKCELMGKLWLQNEVETLEEELRDSPAHVVMSPFVVVDSKALTEYNGIVKSLVRTKKCIVL 1040
Fly 1041 IPNAVLNELDDLKKRSENVRHVIRWLEQEFKQGNRHLRAQRD-NESQPLSLLKISRKMDRDASVF 1104
Fly 1105 LQIAQFCNHLV----ANHADPHVSELQKSVVTYLSG---DNLHEKNRQQQNFSYTGILDSIPVRY 1162
Fly 1163 AQIQSFYAKFK 1173 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Smg5 | NP_001285914.1 | EST1 | 99..222 | CDD:287360 | 36/122 (30%) |
| EST1_DNA_bind | 240..478 | CDD:287359 | 60/272 (22%) | ||
| PIN_Smg5 | 1012..1173 | CDD:189054 | 50/168 (30%) | ||
| SMG5 | NP_056142.2 | EST1 | 77..187 | CDD:287360 | 38/125 (30%) |
| TPR repeat | 172..206 | CDD:276809 | 12/38 (32%) | ||
| EST1_DNA_bind | 197..>412 | CDD:287359 | 59/268 (22%) | ||
| TPR repeat | 211..241 | CDD:276809 | 12/29 (41%) | ||
| TPR repeat | 246..268 | CDD:276809 | 7/21 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 408..561 | 49/215 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 594..637 | 3/42 (7%) | |||
| PIN_Smg5 | 855..1013 | CDD:189054 | 50/168 (30%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165160313 | |
| Domainoid | 1 | 1.000 | 59 | 1.000 | Domainoid score | I10741 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2162 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 196 | 1.000 | Inparanoid score | I3823 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG45620 | |
| OrthoDB | 1 | 1.010 | - | - | D102776at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0008183 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90648 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_107519 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR15696 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5305 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.800 | |||||