| Sequence 1: | NP_723849.1 | Gene: | CenG1A / 34803 | FlyBaseID: | FBgn0028509 | Length: | 995 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055531.1 | Gene: | ACAP1 / 9744 | HGNCID: | 16467 | Length: | 740 | Species: | Homo sapiens |
| Alignment Length: | 588 | Identity: | 141/588 - (23%) |
|---|---|---|---|
| Similarity: | 204/588 - (34%) | Gaps: | 229/588 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 418 SRKSRRRS-------NLFIPSSSKKADKEKEP---KSSELGSGRSIP---------IKQGYLYKR 463
Fly 464 SSKSLNKEWKKKYVTLCDDGRLTYHPSLHD----YMDDVHGKEIPLQYVTVKV-PGQKPRGSKSI 523
Fly 524 ITNSALTSSLMANGQR--------AQNTLSDGIGCLTLAKDNQRKLSEKLSLLGAGSIAAGAGGE 580
Fly 581 PLKSNSSQQTSGDEGIAMSNSNSQTFIAGEVANAGNKLEAQTPNVKKRHRRMKSSSVKANEADDN 645
Fly 646 DGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQR 710
Fly 711 VPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGN 775
Fly 776 SLANSVWESNTRQRV--KPTSQASREDKERWVRSKYEAKEFLTPL--------GNG--------- 821
Fly 822 --SSAHPSPS-----------------PGQQLIEAVIRADIKSIVSILANCPSEVTNANVSA--- 864
Fly 865 --------RDVRTPLLLACAIGNLAIAQLLIWNGANIKHTD--------------HEGRTCLAYA 907
Fly 908 RAA 910 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CenG1A | NP_723849.1 | SelP_N | <5..41 | CDD:282453 | |
| Centaurin_gamma | 143..300 | CDD:133303 | |||
| RAS | 144..295 | CDD:214541 | |||
| PH_AGAP | 451..686 | CDD:241281 | 39/256 (15%) | ||
| PH | 454..>521 | CDD:278594 | 20/80 (25%) | ||
| ArfGap | 702..818 | CDD:279720 | 55/117 (47%) | ||
| ANK | <834..907 | CDD:238125 | 24/97 (25%) | ||
| ANK repeat | 834..866 | CDD:293786 | 7/42 (17%) | ||
| Ank_5 | 859..907 | CDD:290568 | 19/72 (26%) | ||
| ANK repeat | 868..897 | CDD:293786 | 11/28 (39%) | ||
| ACAP1 | NP_055531.1 | Required for formation of endosomal tubules when overexpressed with PIP5K1C | 1..382 | 43/186 (23%) | |
| BAR | 18..217 | CDD:299863 | 3/5 (60%) | ||
| PH | 266..360 | CDD:278594 | 24/103 (23%) | ||
| PH_ACAP | 268..364 | CDD:270070 | 24/105 (23%) | ||
| Required for interaction with GULP1 | 405..740 | 90/359 (25%) | |||
| ArfGap | 406..519 | CDD:279720 | 52/199 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..581 | 9/67 (13%) | |||
| Prevents interaction with ITGB1 when S-554 is not phosphorylated | 525..566 | 5/40 (13%) | |||
| ANK | <592..692 | CDD:238125 | 20/73 (27%) | ||
| ANK repeat | 606..637 | CDD:293786 | 12/30 (40%) | ||
| Ank_5 | 626..680 | CDD:290568 | 12/39 (31%) | ||
| ANK repeat | 639..670 | CDD:293786 | 6/26 (23%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D751525at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R258 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.850 | |||||