DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and GLO3

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_011048.1	Gene:	GLO3 / 856859	SGDID:	S000000924	Length:	493	Species:	Saccharomyces cerevisiae

Alignment Length:	170	Identity:	47/170 - (27%)
Similarity:	71/170 - (41%)	Gaps:	39/170 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   678 EQEIFKSLQSIESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSG 742
            |.|.|.:.|:.:....|..::.:             |..|.|||..||.|.|:..||::||:||.
Yeast     5 EGETFATEQTTQQVFQKLGSNME-------------NRVCFDCGNKNPTWTSVPFGVMLCIQCSA 56

  Fly   743 VHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRS 807
            ||||:|.||:.|:|..||.|...:|......||..|...:..|..:::..|:...       .::
Yeast    57 VHRNMGVHITFVKSSTLDKWTINNLRRFKLGGNHKARDFFLKNNGKQLLNTANVD-------AKT 114

  Fly   808 KYE---AKEFLTPLG----------------NGSSAHPSP 828
            ||.   ||::...|.                ||..:..||
Yeast   115 KYTSPVAKKYKIHLDKKVQKDMELYPSELVLNGQDSSDSP 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281	3/7 (43%)
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	37/118 (31%)
		ANK	<834..907	CDD:238125
		ANK repeat	834..866	CDD:293786
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
GLO3	NP_011048.1	COG5347	9..363	CDD:227651	45/166 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900