Protein Alignment CenG1A and AGD4

DIOPT Version :9

• Sequence 1: NP_723849.1
• Gene: CenG1A / 34803
• FlyBaseID: FBgn0028509
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_001320312.1
• Gene: AGD4 / 837629
• AraportID: AT1G10870
• Length: 780
• Species: Arabidopsis thaliana
• Alignment Length: 600
• Identity: 143/600 - (23%)
• Similarity: 225/600 - (37%)
• Gaps: 214/600 - (35%)

  Fly   432 SSKKADKEKEPKSSELGSGRSIPIKQGYLYKRSSKSLNKEWKKKYVTLCDDGRLTYHPSLHDYMD 496
            :|..||||              .||||||.|||| ||..:||:|:..|...|.:.|:
plant   281 TSLTADKE--------------VIKQGYLLKRSS-SLRTDWKRKFFVLDSHGSMYYY-------- 322

  Fly   497 DVHGKEIPLQYVTVKVPGQKPRGSKSIITNSALTSSLMANGQRAQNTLSDGIGCLTLAKDNQRKL 561
                               :..|:||      :.|....:|....||   |:.....|:.|:
plant   323 -------------------RTNGNKS------MGSHHHYSGSSDHNT---GVFGRFRARHNR--- 356

  Fly   562 SEKLSLLGAGSIAAGAGGEPLKSNSSQQTSGDEGIAMSNSNSQTFIAGEVANAGNKLEAQTPNVK 626
                    :||:..|:.|.                                   |.::.:|..:|
plant   357 --------SGSLTEGSLGY-----------------------------------NTIDLRTSLIK 378

  Fly   627 KRHRRMKSSSVKANEADDNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFKSLQS---- 687
            .             :|:|.|....:.:....|.:..:|.|..:|.:||..:.:.|...|.|
plant   379 L-------------DAEDMDLRLCFRIISPQKTYTLQAENGADRMDWVNKITKAIGTLLNSHFLQ 430

  Fly   688 -------------------------IESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEW 727
                                     |..:.::|....|::.:|   :.:|||..|.:|.||.|:|
plant   431 QSPVRYLDKDNSSSAPANAVVSGDQIRHNDSRQNIGDDVSTIL---RGLPGNNACAECNAPEPDW 492

  Fly   728 ASLNLGVLMCIECSGVHRNLGSHISKVRSLGLD--DWPSPHLSVMLAIGNSLANSVWES------ 784
            ||||||||:||:|||||||||.||||||||.||  .|....|.:...:||...||:||.
plant   493 ASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLDVKVWEPTILDLFRNLGNVYCNSLWEGLLHLDD 557

  Fly   785 -------------NTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHPSPSPGQQLIE 836
                         :.....||..:.|...||:::..||..|..:  :.:.|.|:.|.:  .::.|
plant   558 DCVAFCSEDGSALSHASVSKPCPEDSFSVKEKYILGKYLEKALV--IKDESEANLSAA--SRIWE 618

  Fly   837 AVIRADIKSI---------VSILANCPSEVTN---------ANVSARDVRTP------------- 870
            ||...:|:.|         |:|:.....::|:         |..:.:....|
plant   619 AVQSRNIREIYRLIVTTGDVNIINTKFDDITDIDAYHHIDAAEKAVKKRHDPTVCQRIKESNEPR 683

  Fly   871 --------LLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQA 927
                    |.:||.||:..:.:||:..||::...|:.|||.|.:..::.:...||.:....|
plant   684 SCLQGCSLLHVACHIGDSVLLELLLQFGADLNIRDYHGRTPLHHCISSGNHKFAKILLRRGA--- 745

  Fly   928 GTTIPAPAPPTNGGI 942
                 .|:...:||:
plant   746 -----RPSIEDDGGL 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281	45/234 (19%)
		PH	454..>521	CDD:278594	19/66 (29%)
		ArfGap	702..818	CDD:279720	55/136 (40%)
		ANK	<834..907	CDD:238125	24/111 (22%)
		ANK repeat	834..866	CDD:293786	9/49 (18%)
		Ank_5	859..907	CDD:290568	16/77 (21%)
		ANK repeat	868..897	CDD:293786	10/49 (20%)
AGD4	NP_001320312.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	114	1.000	Domainoid score	I2005
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D751525at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820