DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and AT3G61300

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_191689.1	Gene:	AT3G61300 / 825302	AraportID:	AT3G61300	Length:	972	Species:	Arabidopsis thaliana

Alignment Length:	610	Identity:	99/610 - (16%)
Similarity:	187/610 - (30%)	Gaps:	225/610 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 HPHPQQVHNQLQNPHQNQLPPPQRHN-HAAPTAAASAS--GAPSSSASASASASILVAHPPQPLI 76
            :|.| :|.|.:..   .::|...||. |..||..::.|  |...|............|.|| |::
plant   136 NPSP-KVPNLIST---KKIPSKSRHKFHNIPTNESNHSPRGNQQSFQPQPPPPQSQTALPP-PMM 195

  Fly    77 SNSLAIRQEIQRFESVHPSIYAIYELIDLLPMADAQIAQSIRDHVVCIEDSFVNSQEWTISRSVP 141
            .:||   .:..||.:..|:......                            |..:::|..:.|
plant   196 ESSL---YQAPRFGTPIPTTMGFNP----------------------------NPPDYSIKETKP 229

  Fly   142 DLRLGIVGSLNSGKSALVHRYLTGSYMQEESPEGGRFKKEVFIDGQSYLLL-IRDEGGAPEMQFA 205
                    .|..||.|                   |......::...:|.: |......|.|...
plant   230 --------ILGGGKRA-------------------RSSDHDLVEPMEFLFIKIVKARNLPSMDLT 267

  Fly   206 GWVDAVIFVFSLENEGSFNTVYNYYTKMAHFRNGQEIPMILVGTQDAISERNP---RVIDDTRAR 267
            |.:|..|.|          .:.||..|..||...|                ||   .|...:::.
plant   268 GSLDPYIEV----------KLGNYTGKTKHFEKNQ----------------NPVWNEVFAFSKSN 306

  Fly   268 KLASDLKRCSYYETCATYGLNVERVFQDACQKILSQRLPLPPQVQPARPTTPQGNRLGLAPYQAP 332
            :.::.|:         ...::.:.|..|....|......:|.:|.|..|..|:..|:
plant   307 QQSNVLE---------VIVMDKDMVKDDFVGLIRFDLNQIPTRVAPDSPLAPEWYRV-------- 354

  Fly   333 TNGQRGQQQLPLRMSADFAQAEQKLWSLQAASSSTINENNNITKYNPGAANSLQGDC-------- 389
             |.::|.:   :.::..|.....:.:| .|..|..:|..|.         :||:...
plant   355 -NNEKGGE---IMLAVWFGTQADEAFS-DATYSDALNAVNK---------SSLRSKVYHSPRLWY 405

  Fly   390 SQVQLRDPRDLAPPPGK-ELPTPTSTPTTSRKSRRRSNLFIPSSSKKADKEKEPKSSELGSGRSI 453
            .:|.:.:.:||...|.: .||.|                ::                      .|
plant   406 LRVNVIEAQDLVIVPDRTRLPNP----------------YV----------------------KI 432

  Fly   454 PIKQGYLYKRSSKSLNKEWKKKY----------VTLCDDGRLTYHPSLHDYMDDVH--------- 499
            .:....:..:.|.|||..|.:::          :.:..:.|:.  |:..:.:.:||
plant   433 RLNNQVVRTKPSHSLNPRWNEEFTLVAAEPFEDLIISIEDRVA--PNREETLGEVHIPIGTIDKR 495

  Fly   500 ---GKEIPLQYVTVKVPGQKP--------------RGSKSIITNSALTSS--------LMANGQR 539
               .:.:|.::.::|...|:.              .|...::..|...||        |:::.|.
plant   496 IDDNRTVPNRWFSLKTENQRRVRFATTRLHLNVCLEGGYHVLDESTYYSSDFRPSMKELLSHKQP 560

  Fly   540 AQNTLSDGI----GCLTLAKDNQRK 560
            :...|..||    | |.|:::.:::
plant   561 SFGVLELGILRIEG-LNLSQEGKKE 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453	7/26 (27%)
		Centaurin_gamma	143..300	CDD:133303	25/160 (16%)
		RAS	144..295	CDD:214541	24/154 (16%)
		PH_AGAP	451..686	CDD:241281	25/158 (16%)
		PH	454..>521	CDD:278594	13/102 (13%)
		ArfGap	702..818	CDD:279720
		ANK	<834..907	CDD:238125
		ANK repeat	834..866	CDD:293786
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
AT3G61300	NP_191689.1	C2	6..135	CDD:301316
		C2B_MCTP_PRT_plant	250..370	CDD:176024	30/166 (18%)
		C2C_MCTP_PRT_plant	405..549	CDD:175986	24/183 (13%)
		C2D_MCTP_PRT_plant	564..688	CDD:176025	6/22 (27%)
		PRT_C	816..972	CDD:285560
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910