DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and AGD7

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_001031503.1	Gene:	AGD7 / 818331	AraportID:	AT2G37550	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	337	Identity:	85/337 - (25%)
Similarity:	124/337 - (36%)	Gaps:	115/337 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   701 LAAMLAIR--QRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWP 763
            :||...:|  |..|.|..||||...||:|||::.|:.||:||||.||.||.|||.|||:.:|.|.
plant     1 MAAARRLRTLQSQPENKVCVDCSQKNPQWASISYGIFMCLECSGKHRGLGVHISFVRSVTMDSWS 65

  Fly   764 SPHLSVMLAIGNSLAN---------------SVWESNTRQRVKPTSQASREDKERWVRSKYEAKE 813
            ...:..|.|.||...|               |.:.||.....:...||..|.:: | |.....||
plant    66 EIQIKKMDAGGNERLNNFLAQYGISKETDIISKYNSNAASVYRDRIQALAEGRQ-W-RDPPIVKE 128

  Fly   814 FLTPLGNG-SSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANVSARDVRTPLLLACAI 877
               .:|.| .:..|..|.|                               ..||          .
plant   129 ---SVGGGLMNKKPPLSQG-------------------------------GGRD----------S 149

  Fly   878 GNLAIAQLLIW----NGANIKHTDHE------------GRTCLAYARAAQSLATAKSIKAAAAAQ 926
            ||..      |    |..:.:.||..            ||...|.:::::.:.:...::|:||.:
plant   150 GNGG------WDNWDNDDSFRSTDMRRNQSAGDFRSSGGRGAPAKSKSSEDIYSRSQLEASAANK 208

  Fly   927 ---------AGTTIPAPAPPTNGGI---------PAPQYNVE----DTTALVELLEGLG-----C 964
                     ...:.|...||:.||.         |||:.|.:    |..:::.  ||.|     .
plant   209 ESFFAKRMAENESKPEGLPPSQGGKYVGFGSSPGPAPRSNQQSGGGDVFSVMS--EGFGRLSLVA 271

  Fly   965 PEAAPLTASGTL 976
            ..||.:..:||:
plant   272 ASAANVVQTGTM 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	49/132 (37%)
		ANK	<834..907	CDD:238125	11/88 (13%)
		ANK repeat	834..866	CDD:293786	0/31 (0%)
		Ank_5	859..907	CDD:290568	11/63 (17%)
		ANK repeat	868..897	CDD:293786	4/32 (13%)
AGD7	NP_001031503.1	ArfGap_ArfGap1	3..117	CDD:350059	43/113 (38%)
AGD7	NP_001031503.1	COG5347	5..>258	CDD:227651	76/304 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900