| Sequence 1: | NP_723849.1 | Gene: | CenG1A / 34803 | FlyBaseID: | FBgn0028509 | Length: | 995 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_660256.1 | Gene: | Appl1 / 72993 | MGIID: | 1920243 | Length: | 707 | Species: | Mus musculus |
| Alignment Length: | 561 | Identity: | 112/561 - (19%) |
|---|---|---|---|
| Similarity: | 187/561 - (33%) | Gaps: | 186/561 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 339 QQQLPLR-----MSA---DFAQAEQKLWSLQAASSSTINENNNITKYNPGAANSLQGDCSQVQLR 395
Fly 396 DPRDLAPPPGKELPTPTSTP------TTSRKSRRRSNLFIPSSSKKADKEKEPKSSELGSGRSIP 454
Fly 455 IKQGYLYKRSSKSLNK-EWKKKYVTLCDDGRLTYHPSLHDYMDDVHGKEIPLQYVTVKVPGQKPR 518
Fly 519 GSKSIITNSALTSSLMANGQRAQN----------TLSDGIGCLTLAKDN-------------QRK 560
Fly 561 LSEKLSLLGA----GSIAA--------GAGGEPLKSNSSQQTSGD--EGIAMSNSNSQTFIAGEV 611
Fly 612 ANAGNKLEAQTPNVKKRHRRMKSSSVKANEADDNDGYEFYIVSLDSKQWH-FEAANSEERDEWVA 675
Fly 676 A---VEQEIFKSLQSIE-SSKTKQATSTDLAAMLAIRQR----VPGNGFCVDCGAPNPEWASLNL 732
Fly 733 GVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQ--------- 788
Fly 789 RVKPTSQ---ASREDKERWVRSKYEAKEFLTPLGNGSSAHP 826 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CenG1A | NP_723849.1 | SelP_N | <5..41 | CDD:282453 | |
| Centaurin_gamma | 143..300 | CDD:133303 | |||
| RAS | 144..295 | CDD:214541 | |||
| PH_AGAP | 451..686 | CDD:241281 | 57/276 (21%) | ||
| PH | 454..>521 | CDD:278594 | 13/67 (19%) | ||
| ArfGap | 702..818 | CDD:279720 | 24/131 (18%) | ||
| ANK | <834..907 | CDD:238125 | |||
| ANK repeat | 834..866 | CDD:293786 | |||
| Ank_5 | 859..907 | CDD:290568 | |||
| ANK repeat | 868..897 | CDD:293786 | |||
| Appl1 | NP_660256.1 | Required for RAB5A binding. /evidence=ECO:0000250 | 1..428 | 92/463 (20%) | |
| BAR_APPL1 | 20..234 | CDD:153315 | 45/216 (21%) | ||
| BAR-PH_APPL | 252..376 | CDD:270067 | 32/161 (20%) | ||
| PH | 280..375 | CDD:278594 | 27/132 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 397..433 | 11/53 (21%) | |||
| F&H. /evidence=ECO:0000250 | 403..414 | 2/10 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 466..490 | 3/23 (13%) | |||
| PTB_APPL | 489..624 | CDD:269980 | 6/29 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 636..707 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||