DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenG1A and Smap2

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:NP_598477.2 Gene:Smap2 / 69780 MGIID:1917030 Length:428 Species:Mus musculus


Alignment Length:272 Identity:72/272 - (26%)
Similarity:114/272 - (41%) Gaps:72/272 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   714 NGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLA 778
            |.||.||.:..|.|||.|:||.:||.|:|:|||||.|||:|:|:.||.|....:..|..:||..|
Mouse    25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKA 89

  Fly   779 NSVWESN-----TRQRVKPTSQASREDKERWVRSKYEAKEFLT----------------PLGNGS 822
            |.::|:.     .|.::.|.       .|.::|.|||.|:::.                ..||  
Mouse    90 NRLYEAYLPETFRRPQIDPA-------VEGFIRDKYEKKKYMDRSLDINVLRKEKDDKWKRGN-- 145

  Fly   823 SAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANV---SARDVRTPLL--------LACA 876
                .|:| ::.:|.|:...:|        .|.:..:|.:   |:.....|::        :||:
Mouse   146 ----EPAP-EKKMEPVVFEKVK--------MPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACS 197

  Fly   877 IGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIPAPAPPTNGG 941
            |.|...:..|           .:....||      |:.:..|:...|.....|...|.:.|.|..
Mouse   198 IANSKTSNAL-----------EKDLDLLA------SVPSPSSVSRKAVGSMPTAGSAGSVPENLN 245

  Fly   942 I-PAPQYNVEDT 952
            : |.|....|:|
Mouse   246 LFPEPGSKSEET 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 43/124 (35%)
ANK <834..907 CDD:238125 14/83 (17%)
ANK repeat 834..866 CDD:293786 6/34 (18%)
Ank_5 859..907 CDD:290568 10/58 (17%)
ANK repeat 868..897 CDD:293786 6/36 (17%)
Smap2NP_598477.2 ArfGap 13..126 CDD:307528 43/107 (40%)
Interaction with clathrin heavy chains 163..231 14/84 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 218..262 10/40 (25%)
Med15 276..>416 CDD:312941
Interaction with PICALM. /evidence=ECO:0000269|PubMed:16571680 339..428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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