DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and Arfgap3

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_001344685.1	Gene:	Arfgap3 / 66251	MGIID:	1913501	Length:	525	Species:	Mus musculus

Alignment Length:	156	Identity:	52/156 - (33%)
Similarity:	75/156 - (48%)	Gaps:	36/156 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   700 DLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLD-DWP 763
            |:.|:....:.||.|..|.||||.||.|||::.||.:||:|||.||:||.|:|.:||..|| :|.
Mouse     8 DILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWS 72

  Fly   764 SPHLSVMLAIGNSLANSVW--------ESNT----------RQRVK--PTSQASREDKERWVRSK 808
            ...|..|...|||.|:|.:        ::|.          |:::|  .|....|...:.|:.|
Mouse    73 WFQLRCMQVGGNSNASSFFHQHGCATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLWLDS- 136

  Fly   809 YEAKEFLTPLGNGSSAHP-SPSPGQQ 833
                         .:|.| ||.|.::
Mouse   137 -------------CAAPPVSPPPKEE 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	46/136 (34%)
		ANK	<834..907	CDD:238125	52/156 (33%)
		ANK repeat	834..866	CDD:293786	52/156 (33%)
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
Arfgap3	NP_001344685.1	ArfGap	13..116	CDD:214518	40/102 (39%)
		CDC27	<134..>292	CDD:312868	6/30 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..206
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900