DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenG1A and SMAP2

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:NP_073570.1 Gene:SMAP2 / 64744 HGNCID:25082 Length:429 Species:Homo sapiens


Alignment Length:249 Identity:65/249 - (26%)
Similarity:107/249 - (42%) Gaps:61/249 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   714 NGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLA 778
            |.||.||.:..|.|||.|:||.:||.|:|:|||||.|||:|:|:.||.|....:..|..:||..|
Human    25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKA 89

  Fly   779 NSVWESN-----TRQRVKPTSQASREDKERWVRSKYEAKEFL--------------TPLGNGSSA 824
            |.::|:.     .|.::.|.       .|.::|.|||.|:::              .....||  
Human    90 NRLYEAYLPETFRRPQIDPA-------VEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGS-- 145

  Fly   825 HPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANV---SARDVRTPLL--------LACAIG 878
              .|.|.::| |.|:...:|        .|.:..:..:   |:.....|::        :||:|.
Human   146 --EPVPEKKL-EPVVFEKVK--------MPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIA 199

  Fly   879 NLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIP 932
            |           :...:|..:....||...:..|..:.|.:.:...|.:..::|
Human   200 N-----------SKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVP 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 43/122 (35%)
ANK <834..907 CDD:238125 14/83 (17%)
ANK repeat 834..866 CDD:293786 6/34 (18%)
Ank_5 859..907 CDD:290568 9/58 (16%)
ANK repeat 868..897 CDD:293786 5/36 (14%)
SMAP2NP_073570.1 ArfGap_SMAP2 16..122 CDD:350083 42/103 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 138..184 10/58 (17%)
Interaction with clathrin heavy chains. /evidence=ECO:0000250 163..232 12/79 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 217..259 4/26 (15%)
Interaction with PICALM. /evidence=ECO:0000250 340..429
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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