DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenG1A and AGFG1

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:NP_001128659.1 Gene:AGFG1 / 3267 HGNCID:5175 Length:584 Species:Homo sapiens


Alignment Length:318 Identity:73/318 - (22%)
Similarity:119/318 - (37%) Gaps:61/318 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   690 SSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLG-SHISK 753
            |:|.||....  ..||.....:|.|..|.||....|.:.::.:|..:|..|||..|.|. .|  :
Human     4 SAKRKQEEKH--LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPH--R 64

  Fly   754 VRSLGLDDWPSPHLSVMLAIGNSLANSVWES--NTRQRVKPTSQASREDKERWVRSKYEAKEFLT 816
            |:|:.:..:....:..:...||.:...:|..  :.|....|..:..::.|| :::.|||.|.:..
Human    65 VKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKRWYV 128

  Fly   817 PLGNG---SSAHPSPSPGQQLIEAVIRADIKSIVSILA-NCPSEVTNANVSAR------------ 865
            |....   :|.|.|.| |..........::|.:.|:|. :.|:...|....::            
Human   129 PPEQAKVVASVHASIS-GSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQ 192

  Fly   866 ---------DVRTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKA 921
                     |:.:.:..|.|..:.|.|     |.||..|.:         :.|||:.|.|.....
Human   193 EKKQFDLLSDLGSDIFAAPAPQSTATA-----NFANFAHFN---------SHAAQNSANADFANF 243

  Fly   922 AAAAQAGTTIPAPAPPTN-GGIPAPQYN--VEDTTALVELLEGLGCPE---AAPLTAS 973
            .|..|:..:       :| ||.|...::  ...|||...|.......|   |.||.|:
Human   244 DAFGQSSGS-------SNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQAT 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 29/118 (25%)
ANK <834..907 CDD:238125 14/94 (15%)
ANK repeat 834..866 CDD:293786 5/53 (9%)
Ank_5 859..907 CDD:290568 10/68 (15%)
ANK repeat 868..897 CDD:293786 8/28 (29%)
AGFG1NP_001128659.1 COG5347 8..319 CDD:227651 71/314 (23%)
ArfGap 14..135 CDD:214518 30/123 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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