DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CenG1A and acap3a

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:XP_021325699.1 Gene:acap3a / 322991 ZFINID:ZDB-GENE-030131-1711 Length:845 Species:Danio rerio


Alignment Length:438 Identity:106/438 - (24%)
Similarity:158/438 - (36%) Gaps:169/438 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   632 MKSSSVKANEADDNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFK------------- 683
            ::..|||..| |....:.|.:|| .:|....:|.:.:.|..|:.||:..|..             
Zfish   315 LRLCSVKPCE-DIERRFCFEVVS-PTKSCMLQAESEKLRQAWIQAVQASIASAYRESPDNYYIER 377

  Fly   684 -------SLQSIESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECS 741
                   |:.||:|:...:..|.....:|.....:|||..|.||....|.|||:|||||:|||||
Zfish   378 LDRTASPSISSIDSASESRERSVRGENILQRILSLPGNQQCCDCAQTEPRWASINLGVLLCIECS 442

  Fly   742 GVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQR--VKPTSQASREDKERW 804
            |:||:||.|.||||||.||.|....|.:|..:|||:.|.::|.:..::  .||...:||::||.|
Zfish   443 GIHRSLGVHCSKVRSLTLDSWEPELLKLMCELGNSIINHIYEGSCEEQGLKKPAPNSSRQEKEAW 507

  Fly   805 VRSKYEAKEFLTPLGNG----------------------SSAHPSP--------SPGQQLIEAVI 839
            :::||..|:||..:..|                      :||...|        .||     :..
Zfish   508 IKAKYVEKKFLKKMMTGEVVVNGGRKSERRWNSRKCRRHNSATTVPKTHRKYRQDPG-----SAS 567

  Fly   840 RADIKSIVSILAN--------CPSEVTN------------------------------------- 859
            .|.:.|..:.|..        ||.|:.|                                     
Zfish   568 PATLSSATAALERKFRRESLFCPDELDNLFSYFDTGSGPRSPTGLSSDSGLGGSTDGSTDVLVFE 632

  Fly   860 ----------ANVS---------------------------------ARDV-------------- 867
                      ..||                                 ||::              
Zfish   633 SVVDSVTEEECEVSEDSSNEAELEPEASDPEDSRELDAGALLYKACQARNLPVMAEALAHGADVN 697

  Fly   868 --------RTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYA 907
                    ::||:.|...|:|...:.|:.|.|::...||.||..|.:|
Zfish   698 SVNEEDEGKSPLIQAVIGGSLIACEFLLQNSADVNQRDHRGRGPLHHA 745

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281 16/73 (22%)
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 55/117 (47%)
ANK <834..907 CDD:238125 24/182 (13%)
ANK repeat 834..866 CDD:293786 10/119 (8%)
Ank_5 859..907 CDD:290568 18/149 (12%)
ANK repeat 868..897 CDD:293786 8/28 (29%)
acap3aXP_021325699.1 BAR 16..215 CDD:325158
PH_ACAP 271..367 CDD:270070 15/53 (28%)
ArfGap 403..520 CDD:307528 55/116 (47%)
ANK 674..790 CDD:238125 16/72 (22%)
ANK repeat 674..700 CDD:293786 2/25 (8%)
ANK repeat 702..735 CDD:293786 8/32 (25%)
ANK repeat 737..762 CDD:293786 4/9 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D751525at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

Return to query results.
Submit another query.