DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and Git2

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	XP_017453834.1	Gene:	Git2 / 304546	RGDID:	1359708	Length:	761	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	67/212 - (31%)
Similarity:	106/212 - (50%)	Gaps:	18/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   709 QRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAI 773
            :|:..|..|.||..|:|.|||:|.|.|:|.||..|||:||.|||:||.|....||...|.::..:
  Rat     3 KRLRSNDVCADCSGPDPSWASVNRGTLICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETL 67

  Fly   774 GNSLANSVWESNT---------RQRVKPTSQASREDKERWVRSKYEAKEFL--TPLGNGSSAHPS 827
            .::.|||:||.:.         |::..|..:. ..:|..::|:||:...|:  .|..:..|. .:
  Rat    68 YSNGANSIWEHSLLDPASVMSGRRKANPQDKV-HPNKAEFIRAKYQMLAFVHRLPCRDDDSV-TA 130

  Fly   828 PSPGQQLIEAVIRADIKSIVSILANCPSEVTNAN-VSARDVRTPLLLACAIGNLAIAQLLIWNGA 891
            ....:||..:|...::::.:.:|    |....|| .......|||.:|...|.:..|:||...||
  Rat   131 KDLSKQLHSSVRTGNLETCLRLL----SLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGA 191

  Fly   892 NIKHTDHEGRTCLAYAR 908
            :....|..|:|.:.|||
  Rat   192 DPGTHDSSGKTPVDYAR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	42/119 (35%)
		ANK	<834..907	CDD:238125	19/73 (26%)
		ANK repeat	834..866	CDD:293786	6/32 (19%)
		Ank_5	859..907	CDD:290568	15/48 (31%)
		ANK repeat	868..897	CDD:293786	10/28 (36%)
Git2	XP_017453834.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810