DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and Smap2

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_001094139.1	Gene:	Smap2 / 298500	RGDID:	1308418	Length:	428	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	72/270 - (26%)
Similarity:	114/270 - (42%)	Gaps:	68/270 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   714 NGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLA 778
            |.||.||.:..|.|||.|:||.:||.|:|:|||||.|||:|:|:.||.|....:..|..:||..|
  Rat    25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKA 89

  Fly   779 NSVWESN-----TRQRVKPTSQASREDKERWVRSKYEAKEFL--------------TPLGNGSSA 824
            |.::|:.     .|.::.|.       .|.::|.|||.|:::              .....||
  Rat    90 NRLYEAYLPETFRRPQIDPA-------VEGFIRDKYEKKKYMDRSLDINVLRKEKDDKWKRGS-- 145

  Fly   825 HPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANV---SARDVRTPLL--------LACAIG 878
              .|:| ::.:|.|:...:|        .|.:..:|.:   |:.....|::        :||:|.
  Rat   146 --EPAP-EKKMEPVVFEKVK--------MPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIA 199

  Fly   879 NLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIPAPAPPTNGGI- 942
            |...:..|           .:....||      |:.:..|:...|.....|...|.:.|.|..:
  Rat   200 NSKTSNAL-----------EKDLDLLA------SVPSPSSVSRKAVGSMPTAGSAGSVPENLNLF 247

  Fly   943 PAPQYNVEDT 952
            |.|....|:|
  Rat   248 PEPGSKSEET 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	43/122 (35%)
		ANK	<834..907	CDD:238125	14/83 (17%)
		ANK repeat	834..866	CDD:293786	6/34 (18%)
		Ank_5	859..907	CDD:290568	10/58 (17%)
		ANK repeat	868..897	CDD:293786	6/36 (17%)
Smap2	NP_001094139.1	ArfGap_SMAP2	16..122	CDD:350083	42/103 (41%)
Smap2	NP_001094139.1	PBP1	<102..419	CDD:227507	37/193 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810