| Sequence 1: | NP_723849.1 | Gene: | CenG1A / 34803 | FlyBaseID: | FBgn0028509 | Length: | 995 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036228.1 | Gene: | APPL1 / 26060 | HGNCID: | 24035 | Length: | 709 | Species: | Homo sapiens |
| Alignment Length: | 470 | Identity: | 91/470 - (19%) |
|---|---|---|---|
| Similarity: | 152/470 - (32%) | Gaps: | 160/470 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 418 SRKSRRRSNLFIPSSSKKADKEKEPKSSELGSGRSIPIKQGYLYKRSSKSLNK-EWKKKYVTLCD 481
Fly 482 DGRLTYHPSLHDYMDDVHGKEIPLQYVTVKVPGQKPRGSKSIITNSALTSSLMANGQRAQN---- 542
Fly 543 ------TLSDGIGCLTLAKDN-------------QRKLSEKLSLLGA----GSIAA--------G 576
Fly 577 AGGEPLKSNSSQQTSGD--EGIAMSNSNSQTFIAGEVANAGNKLEAQTPNVKKRHRRMKSSSVKA 639
Fly 640 NEADDNDGYEFYIVSLDSKQWH-FEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAA 703
Fly 704 MLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHR----------NLGSHISKVRSLG 758
Fly 759 LDDWPSPHLSVMLAIGNSLANSVWESNTRQ---------RVKPTSQ---ASREDKERWVRSKYEA 811
Fly 812 KEFLTPLGNGSSAHP 826 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CenG1A | NP_723849.1 | SelP_N | <5..41 | CDD:282453 | |
| Centaurin_gamma | 143..300 | CDD:133303 | |||
| RAS | 144..295 | CDD:214541 | |||
| PH_AGAP | 451..686 | CDD:241281 | 57/273 (21%) | ||
| PH | 454..>521 | CDD:278594 | 13/67 (19%) | ||
| ArfGap | 702..818 | CDD:279720 | 21/137 (15%) | ||
| ANK | <834..907 | CDD:238125 | |||
| ANK repeat | 834..866 | CDD:293786 | |||
| Ank_5 | 859..907 | CDD:290568 | |||
| ANK repeat | 868..897 | CDD:293786 | |||
| APPL1 | NP_036228.1 | Required for RAB5A binding | 1..428 | 73/374 (20%) | |
| BAR_APPL1 | 20..234 | CDD:153315 | 27/123 (22%) | ||
| BAR-PH_APPL | 252..376 | CDD:270067 | 33/162 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 397..434 | 7/53 (13%) | |||
| F&H | 403..414 | 0/13 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 467..491 | 3/23 (13%) | |||
| PTB_APPL | 490..625 | CDD:269980 | 6/29 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 645..709 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||