DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and ucp3

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_596008.1	Gene:	ucp3 / 2540709	PomBaseID:	SPBC21D10.05c	Length:	601	Species:	Schizosaccharomyces pombe

Alignment Length:	129	Identity:	53/129 - (41%)
Similarity:	72/129 - (55%)	Gaps:	4/129 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   706 AIR---QRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHL 767
            |||   |.|.||..|.||.....:|||.|||:.:|:.|:.:||.||:|:|||:|:.||:|.:..:
pombe     9 AIRELVQSVSGNNLCADCSTRGVQWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQI 73

  Fly   768 SVMLAIGNSLANSVWESNTRQRVKPTSQASRED-KERWVRSKYEAKEFLTPLGNGSSAHPSPSP 830
            ..|...||..||..|..|......||:..|.|. .|:::|.|||.|.||....:.:|..||..|
pombe    74 EKMKHWGNINANRYWNPNPLSHPLPTNALSDEHVMEKYIRDKYERKLFLDENHSTNSKPPSLPP 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	49/115 (43%)
		ANK	<834..907	CDD:238125
		ANK repeat	834..866	CDD:293786
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
ucp3	NP_596008.1	COG5347	1..360	CDD:227651	53/129 (41%)
		ArfGap	7..125	CDD:279720	49/115 (43%)
		UBA_like_SF	157..196	CDD:304366
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1799
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810