DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and git-1

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_509761.2	Gene:	git-1 / 181253	WormBaseID:	WBGene00008805	Length:	670	Species:	Caenorhabditis elegans

Alignment Length:	219	Identity:	66/219 - (30%)
Similarity:	96/219 - (43%)	Gaps:	16/219 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   696 ATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLD 760
            |.:.||...|..::       |.|||....||||:..|.::|.||...|..||..:|.:|.|...
Worm     4 AEALDLITSLEQKE-------CDDCGKKEVEWASVKKGTVICSECFCFHSYLGPSVSYLRHLRKS 61

  Fly   761 DWPSPHLSVMLAIGNSLANSVWES----NTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNG 821
            .|...|:.::.|:..|..|.:|||    .:.:..||.:|.....||::|:.|||...|....|..
Worm    62 AWDEEHIRLVHALNTSNTNMIWESALYEGSTKFQKPMAQDPSHIKEQFVKEKYEKLTFQPKRGKD 126

  Fly   822 SSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANVSARDVRTPLLLACAIGNLAIAQLL 886
            .....|.:  :||| |..|:|...:...|....::|...:....|  |.|.:|...||....:||
Worm   127 EDLENSLN--RQLI-ACARSDFAHVTLRLIALGADVNYPDPETGD--TALHVAAREGNSNQVELL 186

  Fly   887 IWNGANIKHTDHEGRTCLAYARAA 910
            ...||:|...:.||......||.|
Worm   187 FLYGADIMAPNREGMLPYILARDA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	37/119 (31%)
		ANK	<834..907	CDD:238125	20/72 (28%)
		ANK repeat	834..866	CDD:293786	7/31 (23%)
		Ank_5	859..907	CDD:290568	13/47 (28%)
		ANK repeat	868..897	CDD:293786	10/28 (36%)
git-1	NP_509761.2	ArfGap	7..127	CDD:214518	40/126 (32%)
		ANK	<122..212	CDD:238125	26/94 (28%)
		Ank_5	152..207	CDD:290568	15/56 (27%)
		ANK repeat	165..197	CDD:293786	11/33 (33%)
		GIT	264..294	CDD:128828
		GIT	326..356	CDD:128828
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810