DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and W09D10.1

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_499364.1	Gene:	W09D10.1 / 176499	WormBaseID:	WBGene00012359	Length:	495	Species:	Caenorhabditis elegans

Alignment Length:	360	Identity:	99/360 - (27%)
Similarity:	139/360 - (38%)	Gaps:	108/360 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   714 NGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLA 778
            |.:|.||.|..|.||:.||||.:||.|:|:|||||.|||||||:.||.|....:..|..:||..|
Worm    29 NKYCADCQAKTPRWAAWNLGVFICIRCAGIHRNLGVHISKVRSVNLDSWTPEQVQTMRVMGNEKA 93

  Fly   779 NSVWESN-TRQRVKPTSQASREDKERWVRSKYEAKEFL--------------------------T 816
            ..|:|.: ..|..:||:.   :..|:::|||||.|.::                          |
Worm    94 RQVYEHDLPAQFRRPTND---QQMEQFIRSKYEQKRYILRDFVYPRVDASQLPKSLSQAQKKVGT 155

  Fly   817 PLGNGSSAHPSPSPGQQLIEAVIRADIKSIVSIL--ANCPSEVTNAN--VSARDVRTPLLLACAI 877
            |:.|.:|...|.|.|.....|...|.     |:|  ::.|:..|.|.  |:..|....|.|..|.
Worm   156 PVVNIASRGSSSSNGHSTASAAAAAP-----SLLDFSDPPASTTPAKKAVNLFDDFDGLSLGPAA 215

  Fly   878 GNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSI--------------KAAAAAQAG 928
            ...|.|.|         :.|.:.......|.:..:...|:|:              .||.:|.:|
Worm   216 PAAAPAAL---------NDDFDDFGSFVSANSQNAQQNAQSLGGGFADFSSAPTTAAAAPSASSG 271

  Fly   929 ----TTIPAPAPPTN------------------GGIPAPQYNVEDTTALVELLEGLGCPEAAP-- 969
                |.:.:.||.||                  |||.||........|      |.|. :|||
Worm   272 LDDLTALSSTAPATNGSDQKKTNADILSLFGPSGGISAPNVVAPGGFA------GFGL-QAAPAQ 329

  Fly   970 ----------LTASGTLPRRRDTLGTPYEKSVSGV 994
                      ..|....|::.|..|     .:||:
Worm   330 IPQQASSFHQFGAPAPAPQQNDMFG-----GLSGI 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281
		PH	454..>521	CDD:278594
		ArfGap	702..818	CDD:279720	48/130 (37%)
		ANK	<834..907	CDD:238125	16/76 (21%)
		ANK repeat	834..866	CDD:293786	8/35 (23%)
		Ank_5	859..907	CDD:290568	10/49 (20%)
		ANK repeat	868..897	CDD:293786	6/28 (21%)
W09D10.1	NP_499364.1	ArfGap_SMAP	20..122	CDD:350068	43/95 (45%)
W09D10.1	NP_499364.1	DEC-1_N	<301..>415	CDD:368028	17/71 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D751525at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820