DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenG1A and F07F6.8

DIOPT Version :9

Sequence 1:	NP_723849.1	Gene:	CenG1A / 34803	FlyBaseID:	FBgn0028509	Length:	995	Species:	Drosophila melanogaster
Sequence 2:	NP_001379858.1	Gene:	F07F6.8 / 173926	WormBaseID:	WBGene00017220	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	71/350 - (20%)
Similarity:	118/350 - (33%)	Gaps:	106/350 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 PRGSKSIITNSALTSSLMANGQRAQNTLSDGIGCLTLAKDNQRK-------LSEKLSLLGAGSIA 574
            ||.....::.:||.:..:                |....:|:||       ::|||.....|...
Worm    32 PRSMSKELSETALRTQFL----------------LDKWSNNRRKIVRQMEGIAEKLDNWEKGCAI 80

  Fly   575 AGAGGEPLKSNSSQQTSGDEGIAMSNS---NSQTFIAGEVANAGNKLEAQTPNVKK-RHRRMKSS 635
            :.|.|..:...|        |||:...   .....|||.:....:.:......:.| .|.:.:..
Worm    81 STAVGSTVGIAS--------GIAVIGGLILMPPVAIAGLIVGTASGVSNLATGITKFFHTKGQHK 137

  Fly   636 SVKANEADDNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAV-----EQEIFKSLQS---IESSK 692
            .|.|..|:|...:|..:.|               |:|.:.||     ::|.||..::   || :|
Worm   138 EVAAMIAEDGVLFEELLKS---------------REELMEAVRKIVEDEEFFKHFKNDGDIE-NK 186

  Fly   693 TKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSL 757
            .|......:..:..|..|                :|..::|.|......||     .|...|..:
Worm   187 LKTVFGGSVTGITGIGTR----------------FAITSMGRLSSSLVKGV-----LHSVAVIGI 230

  Fly   758 GLDDWPSPHLSVMLAIG---------NSLANSVWESNTR---QRVKPTSQASREDKERWVRSKYE 810
            .||       ||.||:.         :.|.:|:.|::::   .|.|.......||.  |    .:
Worm   231 VLD-------SVTLALSAKTLGEGSVSELGSSILEASSKMEMMRQKVVKHFLNEDV--W----KD 282

  Fly   811 AKEFLTPLGNGSSAHPSPSPGQQLI 835
            ..:.|:.:|:.....|. ||.|.||
Worm   283 DDDVLSDVGSIEMVQPE-SPNQSLI 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenG1A	NP_723849.1	SelP_N	<5..41	CDD:282453
		Centaurin_gamma	143..300	CDD:133303
		RAS	144..295	CDD:214541
		PH_AGAP	451..686	CDD:241281	36/184 (20%)
		PH	454..>521	CDD:278594	2/3 (67%)
		ArfGap	702..818	CDD:279720	24/127 (19%)
		ANK	<834..907	CDD:238125	1/1 (100%)
		ANK repeat	834..866	CDD:293786	1/1 (100%)
		Ank_5	859..907	CDD:290568
		ANK repeat	868..897	CDD:293786
F07F6.8	NP_001379858.1	ApoL	<59..>126	CDD:398882	14/74 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900