DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenG1A and Agfg1

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:XP_006496493.1 Gene:Agfg1 / 15463 MGIID:1333754 Length:577 Species:Mus musculus


Alignment Length:290 Identity:65/290 - (22%)
Similarity:108/290 - (37%) Gaps:58/290 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   690 SSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLG-SHISK 753
            |:|.||....  ..||.....:|.|..|.||....|.:.::.:|..:|..|||..|.|. .|  :
Mouse     4 SAKRKQEEKH--LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPH--R 64

  Fly   754 VRSLGLDDWPSPHLSVMLAIGNSLANSVWES--NTRQRVKPTSQASREDKERWVRSKYEAKEFLT 816
            |:|:.:..:....:..:...||.:...:|..  :.|....|..:..::.|| :::.|||.|.:..
Mouse    65 VKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKRWYV 128

  Fly   817 PLGNG---SSAHPSPSPGQQLIEAVIRADIKSIVSILA-NCPSEVTNANVSAR------------ 865
            |....   :|.|.|.| |..........::|.:.|:|. :.|:...|....::            
Mouse   129 PPEQAKVVASVHASIS-GSSASSTSSTPEVKPLKSLLGESAPALHLNKGTPSQSPVVGRSQGQQQ 192

  Fly   866 ---------DVRTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKA 921
                     |:.:.:..|.|..:.|.|     |.||..|.:         :.|||:.|.|.....
Mouse   193 EKKQFDLLSDLGSDIFAAPAPQSTATA-----NFANFAHFN---------SHAAQNSANADFANF 243

  Fly   922 AAAAQAGTT-----IPAPA-----PPTNGG 941
            .|..|:..:     .|..:     |.|.||
Mouse   244 DAFGQSSGSSNFGGFPTASHSSFQPQTTGG 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 29/118 (25%)
ANK <834..907 CDD:238125 14/94 (15%)
ANK repeat 834..866 CDD:293786 5/53 (9%)
Ank_5 859..907 CDD:290568 10/68 (15%)
ANK repeat 868..897 CDD:293786 8/28 (29%)
Agfg1XP_006496493.1 COG5347 8..268 CDD:227651 59/279 (21%)
ArfGap_AGFG1 13..128 CDD:350082 29/119 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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