DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenG1A and acap1

DIOPT Version :9

Sequence 1:NP_723849.1 Gene:CenG1A / 34803 FlyBaseID:FBgn0028509 Length:995 Species:Drosophila melanogaster
Sequence 2:XP_031755514.1 Gene:acap1 / 100496659 XenbaseID:XB-GENE-6257486 Length:783 Species:Xenopus tropicalis


Alignment Length:530 Identity:132/530 - (24%)
Similarity:204/530 - (38%) Gaps:183/530 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   554 AKDNQRKLSEKLSLLGA------GSIAAGAGGEPL-------KSNSSQQTSGDEGIAMSNS---- 601
            |...||.:.:|::|:.|      .|:..|.|.:.:       :::::.:|......::.|:    
 Frog   231 AAREQRDMEQKVTLIKAKDPSDEDSVLQGDGAQVVIEGYLFKRASNTFKTWSRRWFSIQNNQLVY 295

  Fly   602 ----NSQTFIAGEVANAGNKLEAQTPNVKKRHRRMKSSSVKANEADDNDGYEFYIVSLDSKQWHF 662
                :..|.:..::.....||   .|..::|                   :.|.:|| .:|....
 Frog   296 QKKVDVLTVVIVDLRLCAVKL---CPEAERR-------------------FCFEVVS-PAKSCML 337

  Fly   663 EAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDL---------------AAMLAIRQRVP 712
            :|.:......||:||:    :|:.:..|...:::.|..|               .|..|: .|||
 Frog   338 QAESDRVLQLWVSAVQ----RSITTAYSDNKRESGSLRLPRSPAEAPAQEKGVQGAQDAV-LRVP 397

  Fly   713 GNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSL 777
            ||..|.||....|||||:||||.:||||||:||:||.|.||||||.||.|....:.:|..:|||.
 Frog   398 GNASCCDCRTAEPEWASINLGVTLCIECSGIHRSLGVHFSKVRSLTLDSWEPELIKLMCELGNST 462

  Fly   778 ANSVWES-----NTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHP----------S 827
            .|.::|:     |.|   |||:.:||.:||.|:|:||..|:|:|.|...|...|          |
 Frog   463 INGIYEARIEDMNIR---KPTAASSRSEKEVWIRAKYVEKKFITKLPQSSLRSPRHSQPDPPSHS 524

  Fly   828 P--------------------------------SPGQQL-------IE----------------- 836
            |                                |||.|.       ||                 
 Frog   525 PKARTLGQRPNSGPDLKALSRPFAQTELQRPISSPGAQRQNTEETEIEPENGRQVRLRKATRPLL 589

  Fly   837 ------AVIRA------DIKSI-------VSILANCPSEVTNANVSARDVR---------TPLLL 873
                  |..||      |::|:       .::...|...:.:|.....||.         |||:.
 Frog   590 RPKPGLATARAEGADGKDVRSLHPGALLYRAVEHRCLPTMADALAHGADVNWVRSEERGYTPLIR 654

  Fly   874 ACAIGNLAIAQLLIWNGANIKHTDHEGR--------------TCLAYARAAQSLA---TAKSIKA 921
            |....:|..::.|:.|||::..||.:||              .||...|.|...|   :.|.:.:
 Frog   655 AVLSNSLVASEFLLQNGASVNQTDKDGRGPLHHATLQGYTGLACLFLKRGADINAVDNSGKDVLS 719

  Fly   922 AAAAQAGTTI 931
            .|...|...|
 Frog   720 IAIENANADI 729

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenG1ANP_723849.1 SelP_N <5..41 CDD:282453
Centaurin_gamma 143..300 CDD:133303
RAS 144..295 CDD:214541
PH_AGAP 451..686 CDD:241281 26/152 (17%)
PH 454..>521 CDD:278594
ArfGap 702..818 CDD:279720 61/120 (51%)
ANK <834..907 CDD:238125 26/138 (19%)
ANK repeat 834..866 CDD:293786 9/74 (12%)
Ank_5 859..907 CDD:290568 18/70 (26%)
ANK repeat 868..897 CDD:293786 9/37 (24%)
acap1XP_031755514.1 BAR_ACAP1 18..217 CDD:153323
PH_ACAP 266..361 CDD:270070 17/121 (14%)
ArfGap 387..506 CDD:355783 61/122 (50%)
ANKYR <633..734 CDD:223738 24/97 (25%)
ANK repeat 647..678 CDD:293786 9/30 (30%)
ANK repeat 680..711 CDD:293786 7/30 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D751525at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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