DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpII33 and NRPB3

DIOPT Version :9

Sequence 1:	NP_477419.1	Gene:	RpII33 / 34796	FlyBaseID:	FBgn0026373	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_179145.1	Gene:	NRPB3 / 816035	AraportID:	AT2G15430	Length:	319	Species:	Arabidopsis thaliana

Alignment Length:	293	Identity:	118/293 - (40%)
Similarity:	165/293 - (56%)	Gaps:	43/293 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YANQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLAHR 67
            |...|.::|.||.||..||.|.:|::|:||:||||.|:|.||:|||.|::|.||:||:|||:|||
plant     6 YQRFPKIKIRELKDDYAKFELRETDVSMANALRRVMISEVPTVAIDLVEIEVNSSVLNDEFIAHR 70

  Fly    68 IGLIPLISDDVVERLQYTRDCICLD---FCPECSVEFTLDVKCSEEQTRHVTTADLKSSNAKVLP 129
            :|||||.|:..:. ::::|||...|   .|..|||||.|..||..:||..||:.||.|::..|.|
plant    71 LGLIPLTSERAMS-MRFSRDCDACDGDGQCEFCSVEFRLSSKCVTDQTLDVTSRDLYSADPTVTP 134

  Fly   130 VTSRNQGEEDNEYGESNDE--ILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVCFEYDPD-- 190
            |    ....|:...:|::.  |:|:|||:||||||||.|:||.||:||||:|.|.|.|.|:||
plant   135 V----DFTIDSSVSDSSEHKGIIIVKLRRGQELKLRAIARKGIGKDHAKWSPAATVTFMYEPDII 195

  Fly   191 --NSMRHTLYPK---------------------------PDEWPKSEHTELEDDQYEAPYNWEAK 226
              ..|..||..:                           |:.:...|....:.:....|...|..
plant   196 INEDMMDTLSDEEKIDLIESSPTKVFGMDPVTRQVVVVDPEAYTYDEEVIKKAEAMGKPGLIEIS 260

  Fly   227 P--NKFFFNVESAGALKPENIVVMGVQVLKNKL 257
            |  :.|.|.|||.||:|...:|:..:.:||.||
plant   261 PKDDSFIFTVESTGAVKASQLVLNAIDLLKQKL 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpII33	NP_477419.1	RNAP_II_RPB3	7..267	CDD:132909	117/289 (40%)
RpII33	NP_477419.1	RPOLD	19..261	CDD:214766	111/277 (40%)
NRPB3	NP_179145.1	RNAP_II_RPB3	10..302	CDD:132909	117/289 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	177	1.000	Domainoid score	I1078
eggNOG	1	0.900	-	-		E1_COG0202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2017
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1377
OMA	1	1.010	-	-		QHG53541
OrthoDB	1	1.010	-	-		D834009at2759
OrthoFinder	1	1.000	-	-		FOG0004444
OrthoInspector	1	1.000	-	-		otm2753
orthoMCL	1	0.900	-	-		OOG6_101363
Panther	1	1.100	-	-	LDO	PTHR11800
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3150
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840