Protein Alignment Polr2C and rpb3

DIOPT Version :10

• Sequence 1: NP_477419.1
• Gene: Polr2C / 34796
• FlyBaseID: FBgn0026373
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_588324.1
• Gene: rpb3 / 2538816
• PomBaseID: SPCC1442.10C
• Length: 297
• Species: Schizosaccharomyces pombe
• Alignment Length: 276
• Identity: 119/276 - (43%)
• Similarity: 177/276 - (64%)
• Gaps: 25/276 - (9%)

  Fly     5 NQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLAHRIG 69
            ::..:.|..::.::|.|||.:|.|:||||||||.:||.||:|||.|::..|::|:.|||||||:|
pombe     3 SETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLG 67

  Fly    70 LIPLISDDVVE----RLQYTRDCICLDFCPECSVEFTLDVKCSEEQTRHVTTADL-KSSNAKV-L 128
            :|||.|.::.|    .|:|||:|.|..:||:||||..|:.||:.|.|..:...|| .|||:.: .
pombe    68 MIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGH 132

  Fly   129 PVTS--RNQGEEDNEYGESNDEILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVCFEYDPDN 191
            |:.:  :::|.            ||.||||.||:.||..||||..||||||:||:.|.|||||.|
pombe   133 PILADPKSRGP------------LICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDPWN 185

  Fly   192 SMRHTLY----PKPDEWPKSEHTELEDDQYEA-PYNWEAKPNKFFFNVESAGALKPENIVVMGVQ 251
            .::||.|    ....|||||::.:.|:...|. |:|::.:|.:|:.:|||.|::.|..|:|.|::
pombe   186 KLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLR 250

  Fly   252 VLKNKLSNLQTQLSHE 267
            :|:.||:.|...|..|
pombe   251 ILQEKLAVLVRDLDEE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr2C	NP_477419.1	RNAP_II_RPB3	7..267	CDD:132909	118/272 (43%)
rpb3	NP_588324.1	RNAP_II_RPB3	6..266	CDD:132909	118/271 (44%)