DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RpII33 and AgaP_AGAP010321

DIOPT Version :9

Sequence 1:	NP_477419.1	Gene:	RpII33 / 34796	FlyBaseID:	FBgn0026373	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	XP_318245.2	Gene:	AgaP_AGAP010321 / 1278625	VectorBaseID:	AGAP010321	Length:	273	Species:	Anopheles gambiae

Alignment Length:	275	Identity:	234/275 - (85%)
Similarity:	260/275 - (94%)	Gaps:	2/275 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPYANQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLA 65
            |||||||||.|:||||:||||::||||||||||||||||||||||||||||||:|:|||:|||||
Mosquito     1 MPYANQPSVTISELTDENVKFIVEDTELSVANSLRRVFIAETPTLAIDWVQLESNTTVLADEFLA 65

  Fly    66 HRIGLIPLISDDVVERLQYTRDCICLDFCPECSVEFTLDVKCSEEQTRHVTTADLKSSNAKVLPV 130
            ||:||||||||:||:|:||:|||.|||||.||||||||||||:||.||||||||||||:.:||||
Mosquito    66 HRVGLIPLISDEVVDRMQYSRDCPCLDFCNECSVEFTLDVKCNEEHTRHVTTADLKSSDPRVLPV 130

  Fly   131 TSRNQGEEDNEYGESNDEILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVCFEYDPDNSMRH 195
            |||::.:|||||||..||||||||||||||||:|||||||||||||||||.||.|||||||:|||
Mosquito   131 TSRHRDDEDNEYGEGTDEILIIKLRKGQELKLKAYAKKGFGKEHAKWNPTCGVSFEYDPDNAMRH 195

  Fly   196 TLYPKPDEWPKSEHTELEDDQYEAPYNWEAKPNKFFFNVESAGALKPENIVVMGVQVLKNKLSNL 260
            |||||||||||||||||:||:|||.||||.|||||||||||:|||||||||:|||||||||||||
Mosquito   196 TLYPKPDEWPKSEHTELDDDKYEADYNWELKPNKFFFNVESSGALKPENIVLMGVQVLKNKLSNL 260

  Fly   261 QTQLSHESQNDALAV 275
            |||||||:  |.||:
Mosquito   261 QTQLSHET--DVLAI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpII33	NP_477419.1	RNAP_II_RPB3	7..267	CDD:132909	223/259 (86%)
RpII33	NP_477419.1	RPOLD	19..261	CDD:214766	208/241 (86%)
AgaP_AGAP010321	XP_318245.2	RNAP_II_RPB3	7..267	CDD:132909	223/259 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	436	1.000	Domainoid score	I1751
eggNOG	1	0.900	-	-		E1_COG0202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2017
Inparanoid	1	1.050	490	1.000	Inparanoid score	I3132
OMA	1	1.010	-	-		QHG53541
OrthoDB	1	1.010	-	-		D424392at33208
OrthoFinder	1	1.000	-	-		FOG0004444
OrthoInspector	1	1.000	-	-		oto107648
Panther	1	1.100	-	-	LDO	PTHR11800
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3150
TreeFam	1	0.960	-	-
	13	12.940