Protein Alignment Orc5 and orc-5

DIOPT Version :9

• Sequence 1: NP_477132.1
• Gene: Orc5 / 34794
• FlyBaseID: FBgn0015271
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001366775.1
• Gene: orc-5 / 177964
• WormBaseID: WBGene00013857
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 107/450 - (23%)
• Similarity: 184/450 - (40%)
• Gaps: 106/450 - (23%)

  Fly    35 SAIYLFGHSGTGKTALTRAFLKECGKRQNVRTAHLNAIECYTTKIMLEILLDSLAPDQGDALKVD 99
            |.:::||..|:|::.:.|..|:   |.:|.....|.  :.......|::|.||||...|...:.|
 Worm    21 SHVHIFGEDGSGRSEIVRQLLR---KPENDWVCVLG--DFLYADGSLKLLFDSLASSLGFKTRGD 80

  Fly   100 NMLDFVEQLRRQAATRVE-DQGFLIAVDNAERLRDMDANVLPVLLR--------LQELT------ 149
            ...:|.:.|.:......| ::..:|.:|||:.:.|..    ||.|:        :||:|
 Worm    81 RAENFCDNLYKYVQWPDETNRKIVIFLDNAQAITDYP----PVPLQCLFDSYKAIQEITIRFVTS 141

  Fly   150 ---NLNLCVILLSQLPFEKFYNKTGLSEIVCLHLAQYNKAETQRILGSDFQQVRNQLLEQFAQDK 211
               .||...|.||.||..:|            |:...:...|:.::.....::..|.|....|
 Worm   142 APSCLNQYHINLSHLPVVEF------------HIPAPSVETTKVLISRANPKINAQFLHVACQ-- 192

  Fly   212 KRLEICQEAVTEDFYNNYLNLFLSV------FYKACRDVPELQLT-ARKCLSTYLEPVLDGTVDA 269
            .....|:..          |:.||:      .|...|...:...| |::||:......|...|.
 Worm   193 SLFMACKSP----------NILLSIISDAWLMYDERRTGDKFDSTLAKECLNRSSGEKLGNVVG- 246

  Fly   270 TDISRLWRHIAGPLRSALTQIYMRIEKPAEEVED-FTAIEDQSVRKLAQSLELPYYAKFLLIAAF 333
                                     |..|:|.|: |.|              :|...::|||||:
 Worm   247 -------------------------ENLAKENENSFDA--------------MPLAMRYLLIAAY 272

  Fly   334 LASHNAAKQDKRLFVKHHGKQRKRMQTVNARAKTTEKMSTTLGPKSFSIDRLLAIFYAILE--EK 396
            .||:|..:.|.|.|||:||:: ||.:....|.: ..:::..||||:..:.|::.|:..:|:  |.
 Worm   273 CASNNPHQSDCRFFVKNHGRE-KRSEKKELRLE-ENRLAKDLGPKAADLQRIICIYETLLKINES 335

  Fly   397 VGLTCNLLSQISTLVHLNLLSFVSGEQNIMEGSARLQCTIGLEFVLQIGKVVGFNVRQYL 456
            .....:|.|.|::|..:.|:| |:...|:  ...:::|.|.||..|:|.:.:...:|.||
 Worm   336 TITGFDLKSVIASLDSMGLVS-VTNRSNL--DIPKIKCLISLESALKISRSLNLELRNYL 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc5	NP_477132.1	CDC6	12..>159	CDD:224391	35/141 (25%)
		AAA_16	12..151	CDD:289934	32/133 (24%)
		ORC5_C	178..456	CDD:291304	65/287 (23%)
orc-5	NP_001366775.1	AAA_16	5..111	CDD:404141	24/94 (26%)
		ORC5_C	162..392	CDD:405335	65/286 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I3573
Isobase	1	0.950	-	0.919607	Normalized mean entropy	S4134
OMA	1	1.010	-	-		QHG52064
OrthoDB	1	1.010	-	-		D438169at33208
OrthoFinder	1	1.000	-	-		FOG0004930
OrthoInspector	1	1.000	-	-		oto18666
orthoMCL	1	0.900	-	-		OOG6_103513
Panther	1	1.100	-	-	LDO	PTHR12705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R874
SonicParanoid	1	1.000	-	-		X5263
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.890