Protein Alignment Orc5 and Orc5

DIOPT Version :10

• Sequence 1: NP_477132.1
• Gene: Orc5 / 34794
• FlyBaseID: FBgn0015271
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_309174.2
• Gene: Orc5 / 1270475
• VectorBaseID: AGAMI1_010709
• Length: 464
• Species: Anopheles gambiae
• Alignment Length: 474
• Identity: 232/474 - (48%)
• Similarity: 319/474 - (67%)
• Gaps: 26/474 - (5%)

  Fly     1 MEAICSSLEPLFPCREAAIETLGELI--GDSSETYPSAIYLFGHSGTGKTALTR-AFLKECGKRQ 62
            |||....:..:.|||:..:..|....  ||.   :|.|:|::|.|.|||.|:.| .|.......:
Mosquito     1 MEAFVKQIAGVLPCRDGYVRQLYRYYRKGDQ---FPPALYIYGQSSTGKGAILREVFRCRSAADE 62

  Fly    63 NVRTAHLNAIECYTTKIMLEIL---LDSLAPDQGDALKVDNMLDFVEQLRRQAATRVED-QGFLI 123
            ::|.|.|:||.|||.||:.|.:   |:.....|.:...:|..|::.:........|::. :.::|
Mosquito    63 SLRCAQLSAISCYTNKILFETIVRQLEGAELSQSNHYSIDCKLEYAKDFLAALRQRLDPARSYVI 127

  Fly   124 AVDNAERLRDMDANVLPVLLRLQELTNLNLCVILLSQLPFEKFYNKTGLSEIVCLHLAQYNKAET 188
            .|.:|||||||..|:||:.|:|.|.|.||:.|:|:|.|||||||.|.||..:|.|.:|:|.:|:.
Mosquito   128 VVRHAERLRDMAHNLLPLFLQLPEATGLNVSVVLVSSLPFEKFYTKAGLPPVVKLFVAEYTRADM 192

  Fly   189 QRILGSDF-QQVRNQLLEQFAQDKKRLEICQEAVTEDFYNNYLNLFLSVFYKACRDVPELQLTAR 252
            ||||.:|: ..|:....::.|.|    ::...|:||:|:.||::|||..|:|.||||.||:|.|.
Mosquito   193 QRILMNDYAPHVQGLGGQRSAPD----QLWLAAITEEFHRNYVSLFLGTFWKVCRDVKELRLVAA 253

  Fly   253 KCLSTYLEPVLDGTVDATDISRLWRHIAGPLRSALTQIYMRIEKPAEEVEDFTAIEDQSVRKLAQ 317
            :|...|.|||.|||:.|.|..:|||:|...||:||:.:||||...|..    :.:.......|||
Mosquito   254 ECFPAYCEPVRDGTIPAHDSMKLWRNITKTLRAALSTMYMRIGTKATG----SGVAPDGTAWLAQ 314

  Fly   318 SLELPYYAKFLLIAAFLASHNAAKQDKRLFVKHHGKQRKRMQTVNARAKTTEKMSTTLGPKSFSI 382
            :||||||||:|||||:|||:||||:|:|||:|:|||||||||.||||||.||||:|.||||:|::
Mosquito   315 NLELPYYAKYLLIAAYLASNNAAKEDRRLFMKNHGKQRKRMQAVNARAKVTEKMTTKLGPKAFNV 379

  Fly   383 DRLLAIFYAILEEKVGLTCNLLSQISTLVHLNLLSFVS------GEQNIMEGSA-RLQCTIGLEF 440
            |||||||||||:|:||||||||:||||||||.||::.|      |...:::||| |||||:|::|
Mosquito   380 DRLLAIFYAILDEQVGLTCNLLAQISTLVHLKLLTYASSAEGGAGGSAMLDGSATRLQCTVGMDF 444

  Fly   441 VLQIGKVVGFNVRQYLCDF 459
            :||||::|||||||||.||
Mosquito   445 ILQIGRMVGFNVRQYLTDF 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc5	NP_477132.1	AAA_16	12..151	CDD:433025	49/145 (34%)
		ORC5_C	178..456	CDD:464224	160/285 (56%)
Orc5	XP_309174.2	AAA_16	12..155	CDD:433025	51/149 (34%)
		ORC5_C	182..460	CDD:464224	162/286 (57%)