Protein Alignment Arpc1 and ARPC1A

DIOPT Version :10

• Sequence 1: NP_476596.1
• Gene: Arpc1 / 34793
• FlyBaseID: FBgn0001961
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_006400.2
• Gene: ARPC1A / 10552
• HGNCID: 703
• Length: 370
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 209/362 - (57%)
• Similarity: 264/362 - (72%)
• Gaps: 5/362 - (1%)

  Fly    11 LASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNRIVSCAA 75
            |..|||||||:|||||||||||||:|||.:.||.|..|..|.:|:..:.|||||..::|||:|.|
Human     8 LEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDWAPKSDRIVTCGA 72

  Fly    76 DRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESENDWWVSKH 140
            |||||||:| .||.|||.||:||||||||.|||||.|||||||||||||||||||||||||||||
Human    73 DRNAYVWSQ-KDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKH 136

  Fly   141 IKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIEEPPTPTPWGNRKPLGQLMAEFRNS 205
            |||||||||.|||||||||||.|||.|:|.|||||:||:::|.|..||||::.|.||||:||..|
Human   137 IKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGS 201

  Fly   206 QTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPTSVVVAG 270
            .|  |||::.||||:.|:::.||.|||.||:|||:....|...:|.:||.||..:||..|||.||
Human   202 GT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAG 264

  Fly   271 YSCVPLLYSLTADGKLVLSGKLDKSQKKESSGITAMRIFQSMDRNMRTENTDTVVDSIHQNAITS 335
            :.|.|:|::....|.|....|||..::.....::||..|::||:...||:.:|.::::|||:||.
Human   265 HDCCPMLFNYDDRGCLTFVSKLDIPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQ 329

  Fly   336 VRLYAGDKASATKVSTSGVDGQLVIWNVE--QGGING 370
            |.:|..||....|..|:|:||.:.||:.:  :..|.|
Human   330 VSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQG 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arpc1	NP_476596.1	WD40	<3..236	CDD:475233	158/224 (71%)
		WD40 repeat	14..53	CDD:293791	28/38 (74%)
		WD40 repeat	59..97	CDD:293791	25/37 (68%)
		WD40 repeat	103..142	CDD:293791	36/38 (95%)
		WD40	146..>366	CDD:475233	105/221 (48%)
		WD40 repeat	150..203	CDD:293791	35/52 (67%)
		WD40 repeat	213..247	CDD:293791	16/33 (48%)
ARPC1A	NP_006400.2	WD 1	6..45		27/36 (75%)
		WD40 repeat	11..50	CDD:293791	28/38 (74%)
		WD40	<15..266	CDD:441893	170/253 (67%)
		WD 2	50..89		23/39 (59%)
		WD40 repeat	56..93	CDD:293791	25/37 (68%)
		WD40 repeat	98..138	CDD:293791	37/39 (95%)
		WD 3	140..179		29/38 (76%)
		WD40 repeat	146..199	CDD:293791	35/52 (67%)
		WD 4	202..241		20/40 (50%)
		WD40 repeat	207..243	CDD:293791	16/35 (46%)
		WD 5	244..284		17/39 (44%)
		WD40 repeat	249..287	CDD:293791	15/37 (41%)
		WD 6	322..365		16/42 (38%)