DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc1 and LOC100488540

DIOPT Version :9

Sequence 1:	NP_476596.1	Gene:	Arpc1 / 34793	FlyBaseID:	FBgn0001961	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_002943496.2	Gene:	LOC100488540 / 100488540	-ID:	-	Length:	357	Species:	Xenopus tropicalis

Alignment Length:	360	Identity:	184/360 - (51%)
Similarity:	257/360 - (71%)	Gaps:	7/360 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YTFGTSLASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNR 69
            |:|||.  .|:|||||:||||:|:||||:.:.||.|..::||....|.:|:.||.|||||..:||
Frog     4 YSFGTD--PISCHAWNQDRTQVAISPNNNLVQIYQRSDNEWKKIHELTEHNGRVTGIDWAPTSNR 66

  Fly    70 IVSCAADRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESEND 134
            :|:||||||||||:. .||.|||.|||||||||||||||||.|||.|||||:::|||||||.|||
Frog    67 LVTCAADRNAYVWSL-RDGAWKPTLVLLRINRAATCVKWSPRENKLAVGSGSKIISVCYFEKEND 130

  Fly   135 WWVSKHIKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIEEPPTPTPWGNRKPLGQLM 199
            ||:||||||.|.||:.||.||||||||.|||:|::.||||.::|:|::.|:||.||.:.|.|:|:
Frog   131 WWLSKHIKKSIGSTILSLAWHPNNVLLAAGSSDFQCRVFSGYVKEIDDKPSPTHWGTKIPFGELL 195

  Fly   200 AEFRNSQTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPT 264
              |::.:.  |||::.|:||..|..:.||.|:||||:||:.....|.|..|.||||||..:|:..
Frog   196 --FQSGEK--GGWVHGVAFSPSGRYLAWVDHNSCVSVADSAEDKAVTRLSTEYLPFLSLLFVNEC 256

  Fly   265 SVVVAGYSCVPLLYSLTADGKLVLSGKLDKSQKKESSGITAMRIFQSMDRNMRTENTDTVVDSIH 329
            .::.||:.|.|.|:|....|||....|:|..::...:.::||..|:::|:....|:..:.|.::|
Frog   257 QLLAAGHDCAPYLFSYGGSGKLDFEAKIDVQKETTKTALSAMSHFRNLDKKGAKESERSDVTTLH 321

  Fly   330 QNAITSVRLYAGDKASATKVSTSGVDGQLVIWNVE 364
            ||:|:.:.:..||.:..|..|::|:||.||||:::
Frog   322 QNSISQLSIVDGDPSDVTAFSSTGIDGALVIWSLK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc1	NP_476596.1	WD40	<3..236	CDD:295369	139/230 (60%)
		WD40	<3..181	CDD:225201	116/175 (66%)
		WD40 repeat	14..53	CDD:293791	21/38 (55%)
		WD40 repeat	59..97	CDD:293791	25/37 (68%)
		WD40 repeat	103..142	CDD:293791	31/38 (82%)
		WD40	146..>366	CDD:295369	89/219 (41%)
		WD40 repeat	150..203	CDD:293791	28/52 (54%)
		WD40 repeat	213..247	CDD:293791	14/33 (42%)
LOC100488540	XP_002943496.2	WD40 repeat	11..50	CDD:293791	21/38 (55%)
		WD40	45..>264	CDD:392136	130/223 (58%)
		WD40 repeat	56..94	CDD:293791	26/38 (68%)
		WD40 repeat	99..138	CDD:293791	31/38 (82%)
		WD40 repeat	146..198	CDD:293791	29/53 (55%)
		WD40 repeat	205..242	CDD:293791	15/36 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	183	1.000	Domainoid score	I3367
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	441	1.000	Inparanoid score	I1613
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D317177at33208
OrthoFinder	1	1.000	-	-		FOG0001692
OrthoInspector	1	1.000	-	-		otm48305
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R87
SonicParanoid	1	1.000	-	-		X1085
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090