Protein Alignment PolG1 and POLGAMMA1

DIOPT Version :10

• Sequence 1: NP_476821.1
• Gene: PolG1 / 34792
• FlyBaseID: FBgn0004406
• Length: 1145
• Species: Drosophila melanogaster
• Sequence 2: NP_001189942.1
• Gene: POLGAMMA1 / 821600
• AraportID: AT3G20540
• Length: 1049
• Species: Arabidopsis thaliana
• Alignment Length: 1011
• Identity: 205/1011 - (20%)
• Similarity: 308/1011 - (30%)
• Gaps: 369/1011 - (36%)

  Fly   225 LEPLDVDTDSERPHY---TTDELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSL 286
            |:||:.||..:...|   .|...:...|         |:|..||.||:.|    ...|.||.:|
plant   216 LKPLNSDTTLDNASYKKTATISKVEKCT---------NLSQVRANLKKIY----NRVRVVDNVS- 266

  Fly   287 HMCVSGVTSYQRAMLKSKKEPAAEDLGWLEQSSLNSLV-----EVHRLYCGGDTLSKEPRNIFVE 346
                            |.||..|     |..:...:||     ||.|:    |..::.|.:   .
plant   267 ----------------SAKETVA-----LLMNQYRNLVHACDTEVSRI----DVKTETPVD---H 303

  Fly   347 GTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSNWERY 411
            |  |.:..|.     ||.|:.:                |....|...:..:|       .|....
plant   304 G--EMICFSI-----YCGSEAD----------------FGDGKSCIWVDVLG-------ENGRDI 338

  Fly   412 IREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQNLW---------------LWDED----- 456
            :.|.:..:||.||:..:|         :...|:...:|..               |||..
plant   339 LAEFKPFFEDSSIKKVWH---------NYSFDNHIIRNYGIKLSGFHGDTMHMARLWDSSRRISG 394

  Fly   457 -WSVQELKLKQPPKRKPLPTVELKDSGNTPEERRLQAK--FQHLYDQQALLPARRPLLPGYPLWY 518
             :|::  .|...||        :.....|.||..|..|  .:.::.:..|   ::....|
plant   395 GYSLE--ALTSDPK--------VLGGTETKEEAELFGKISMKKIFGKGKL---KKDGSEG----- 441

  Fly   519 RKLCRKPPAKRADEILEDDEEPW--SPGASEIST-------------------GMQIAPKLLSLC 562
             ||...||.|   |:..:|.|.|  ......|||                   |..|:.|.:
plant   442 -KLVIIPPVK---ELQMEDREAWISYSALDSISTLKLYESMKKQLQAKKWFLDGKLISKKNM--- 499

  Fly   563 WEGYPLHYEREQGWGFLVPFRSDSEG--VDR---------LPMEQLLA----------HCPVPE- 605
               :..:.|..|.:|.|:. :.:|||  |||         ...||.:|          |||..:
plant   500 ---FDFYQEYWQPFGELLA-KMESEGMLVDRDYLAQIEIVAKAEQEIAVSRFRNWASKHCPDAKH 560

  Fly   606 -------------FARLSASKAESDMAFDML---PG---QVEQHLGKREHYKKLSQKQQRLE--- 648
                         |..:|.|..:.|:.::.|   |.   .:|:  ||:...|..:.|..|:.
plant   561 MNVGSDTQLRQLFFGGISNSCNDEDLPYEKLFKVPNVDKVIEE--GKKRATKFRNIKLHRISDRP 623

  Fly   649 ---TQYQGSGVW---------------------CNKVLDDC---------CFFLKLPHKNGPSFR 680
               .::..|| |                     ...|||.|         |  :.||.:...:..
plant   624 LPTEKFTASG-WPSVSGDTLKALAGKVSAEYDYMEGVLDTCLEENIGDDDC--ISLPDEVVETQH 685

  Fly   681 VGNPLSKD------FLNKFAENVLSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVVWLDSQ 739
            |...:..|      ..:.|...  .||..:|.|.|.:.::..:        |.::...::.|...
plant   686 VNTSVESDTSAYGTAFDAFGGG--ESGKEACHAIAALCEVCSI--------DSLISNFILPLQGS 740

  Fly   740 QLPNEFTGEKCQPIAYGAICPQVVACGTLTRR--AMEPTWMTASNSRPDRLGSELRSMVQAPPGY 802
            .:..:.....|.           :...|.|.|  |..|..........||.  ::|....|.||.
plant   741 NVSGKDGRVHCS-----------LNINTETGRLSARRPNLQNQPALEKDRY--KIRQAFIASPGN 792

  Fly   803 RLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVI 867
            .|:.||....||.|.:.|....:..|             :...|.|.||.||..:
plant   793 SLIVADYGQLELRILAHLASCESMKE-------------AFIAGGDFHSRTAMNM---------- 834

  Fly   868 NYARIYGA---GQLFAE------------TLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRL-- 915
             |..|..|   |::..|            .||:.   .|::...||| |..|||..||....|
plant   835 -YPHIREAVENGEVLLEWHPQPGQEKPPVPLLKD---AFASERRKAK-MLNFSIAYGKTAIGLSR 894

  Fly   916 -----REE--------FHDELEDRAYSSYEASRLAIQRNRTLAEVFHRPNWQGGTESAMFNRLEE 967
                 |||        ::|..|.|.:.... .:.|||:...|..:.....:......|..|.:|.
plant   895 DWKVSREEAQDTVNLWYNDRQEVRKWQELR-KKEAIQKGYVLTLLGRARKFPEYRSRAQKNHIER 958

  Fly   968 IATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGSHVR 1032
            .|.    .||..|.....|:.|.......||                     |..:.|      :
plant   959 AAI----NTPVQGSAADVAMCAMLEISNNQR---------------------LKELGW------K 992

  Fly  1033 FCLSFHDELRYLVKEELSPKAALAMHI-TNLMTRSF 1067
            ..|..|||   ::.|..|..|..|..| .|.|:..|
plant   993 LLLQVHDE---VILEGPSESAENAKDIVVNCMSEPF 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PolG1	NP_476821.1	DNApol_Exo	107..381	CDD:465664	37/163 (23%)
		DNA_pol_A	398..>440	CDD:470638	8/41 (20%)
		DNA_pol_gammaA	705..1107	CDD:176478	84/396 (21%)
POLGAMMA1	NP_001189942.1	DNA_polA_I_Ecoli_like_exo	279..516	CDD:176651	58/311 (19%)
		DNA_pol_A_plastid_like	633..1047	CDD:176477	98/482 (20%)