Protein Alignment tam and DNApol-theta

DIOPT Version :9

• Sequence 1: NP_476821.1
• Gene: tam / 34792
• FlyBaseID: FBgn0004406
• Length: 1145
• Species: Drosophila melanogaster
• Sequence 2: NP_524333.1
• Gene: DNApol-theta / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Alignment Length: 1200
• Identity: 217/1200 - (18%)
• Similarity: 365/1200 - (30%)
• Gaps: 461/1200 - (38%)

  Fly     6 IRKYASKVSREHYASSSVKIFRRVKPPQKVNKPKKPENVENGPTEYAENLVKVQMISRNLHAQLF 70
            |:|..|::.:.....::|     |..||..|: :||...::.    ...||...|..|. ...|.
  Fly  1147 IQKQGSQIEKMKINPATV-----VCSPQLANE-EKPSTSQSA----RRKLVNEGMAERR-RVALM 1200

  Fly    71 PQAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPY 135
            ....|:..|.|      .||:..:.....:.|:||:    :.||.|....|           .|.
  Fly  1201 KIQQRTQKENQ------SKDQPIQASRSNQLSSPVN----RTPANRWTQSE-----------NPN 1244

  Fly   136 EELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATP---------VDHPLEKGLVFDVEVCVS 191
            .|:     ...|||:|             :|.:.:..|         |.:..|...:.|....::
  Fly  1245 NEM-----NNSQLPRR-------------NPRNQSPVPNANRTASRKVSNAEEDLFMADDSFMLN 1291

  Fly   192 EGQAPVLATAVSTKRWYSWVSSKLTKHRLSVEKLEPLDVDTDSE----------RPHYT----TD 242
            .|.|..|..|.|                 .:......||...|:          .||.:    :|
  Fly  1292 TGLAAALTAAES-----------------KIASCTEADVIPSSQPKEPEVIGALTPHASRLKRSD 1339

  Fly   243 ELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMS---------LHMCVSGVTSYQR 298
            :|.......|.......:..|   |:.:..:....:..:..||         ||:..|.:.|.
  Fly  1340 QLRSQRIQSPSPTPQREIEID---LESKNESNGVSSMEISDMSMENPLMKNPLHLNASHIMSC-- 1399

  Fly   299 AMLKSKKEPAAEDLGWLEQSSLNS--LVEVHRLYCGGDTLSKEPRNIFVEGTLE----------- 350
                ||.:..|        ||.:|  :::|    ||       .||.|....:|
  Fly  1400 ----SKVDETA--------SSFSSIDIIDV----CG-------HRNAFQAAIIEINNATRLGFSV 1441

  Fly   351 --QVRQSFQS-------LTNY--CASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPV 404
              |.:...|.       |.|.  .|.:.||..| .|||:.:....|....|..  |....||.
  Fly  1442 GLQAQAGKQKPLIGSNLLINQVAAAENREAAAR-ERVLFQVDDTNFISGVSFC--LADNVAYY-- 1501

  Fly   405 NSNWERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQNLWLWDEDWSVQELKLKQPPK 469
               |...|.| :..|:.:....|      .:|.|:|:.    |::|.|...| ..::||:    .
  Fly  1502 ---WNMQIDE-RAAYQGVPTPLK------VQELCNLMA----RKDLTLVMHD-GKEQLKM----L 1547

  Fly   470 RKPLPTVELKDSGNTPEERRLQAKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEIL 534
            ||.:|.:           :|:.||.:                              .||.|:.:|
  Fly  1548 RKAIPQL-----------KRISAKLE------------------------------DAKVANWLL 1571

  Fly   535 EDDEEPWSPGASEISTGMQIAPK---LLSLCWEGYPLHYEREQGWGFLVPFRSDSEGVDR----L 592
            :.|:.     .:.::.....||:   |.:||..|        :|:        .|.|:|.    |
  Fly  1572 QPDKT-----VNFLNMCQTFAPECTGLANLCGSG--------RGY--------SSYGLDTSSAIL 1615

  Fly   593 PMEQLLAHCPVPEFARLSASKAESDMAFDMLPGQVE--QHLGKREHYK-----------KLSQ-- 642
            |              |:..: .||.:...:|.||.|  ..:|..:..|           .|.|
  Fly  1616 P--------------RIRTA-IESCVTLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQME 1665

  Fly   643 ------KQQRLETQYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSG 701
                  ::|||:..||.......||      ..|:..::|..|.:|
  Fly  1666 LVGFPAQKQRLQQLYQRMVAVMKKV------ETKIYEQHGSRFNLG------------------- 1705

  Fly   702 DPSCQAAARVIDIAR-----------------------MMSYWRNN---------------RDRI 728
              |.||.|:|:.:.|                       ::.|.:.:               .|||
  Fly  1706 --SSQAVAKVLGLHRKAKGRVTTSRQVLEKLNSPISHLILGYRKLSGLLAKSIQPLMECCQADRI 1768

  Fly   729 MGQMVVWL----------DSQQLPNEFTGEKCQPIAYGAICPQVVACGTLTRRAMEPTWMTASNS 783
            .||.:.:.          :.|.:..||:.:....:.:       ::|    |....||..:....
  Fly  1769 HGQSITYTATGRISMTEPNLQNVAKEFSIQVGSDVVH-------ISC----RSPFMPTDESRCLL 1822

  Fly   784 RPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSD 848
            ..|....|:|.:........|:.....||:|:|        |...|      |..:..|:.. .|
  Fly  1823 SADFCQLEMRILAHMSQDKALLEVMKSSQDLFI--------AIAAH------WNKIEESEVT-QD 1872

  Fly   849 MHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVY 913
            :           |:..|.:.|..:||.|       :|....:.:.||.:|:
  Fly  1873 L-----------RNSTKQVCYGIVYGMG-------MRSLAESLNCSEQEAR-------------- 1905

  Fly   914 RLREEFHDELEDRAYS---SYEASRLAIQRNRTLAEVFHRPNWQGGTESAMFNRLEEIATGSQPR 975
            .:.::||     :||.   .|....:...|::...|          |.:.....||.|.:
  Fly  1906 MISDQFH-----QAYKGIRDYTTRVVNFARSKGFVE----------TITGRRRYLENINS----- 1950

  Fly   976 TPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSM---------RWLMGSH- 1030
                        :.:....|.:|   ..:|..:|..|.|.....::.|         :..:|.:
  Fly  1951 ------------DVEHLKNQAER---QAVNSTIQGSAADIAKNAILKMEKNIERYREKLALGDNS 2000

  Fly  1031 VRFCLSFHDELRYLVKEELSPKAALAMHIT 1060
            |...:..||||.:.|....:.|.|..:.:|
  Fly  2001 VDLVMHLHDELIFEVPTGKAKKIAKVLSLT 2030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tam	NP_476821.1	DNA_pol_A	398..>440	CDD:295402	9/41 (22%)
		TRH	<420..539	CDD:283171	21/118 (18%)
		DNA_pol_gammaA	705..1107	CDD:176478	68/416 (16%)
DNApol-theta	NP_524333.1	BRR2	209..978	CDD:224125
		DEAD	251..404	CDD:278688
		HELICc	542..616	CDD:197757
		PolA	1489..2055	CDD:223820	132/761 (17%)
		DNA_pol_A_theta	1668..2053	CDD:176475	80/482 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0749
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900