Protein Alignment tam and polg

DIOPT Version :9

• Sequence 1: NP_476821.1
• Gene: tam / 34792
• FlyBaseID: FBgn0004406
• Length: 1145
• Species: Drosophila melanogaster
• Sequence 2: XP_002932281.3
• Gene: polg / 100488393
• XenbaseID: XB-GENE-478798
• Length: 1197
• Species: Xenopus tropicalis
• Alignment Length: 1214
• Identity: 513/1214 - (42%)
• Similarity: 700/1214 - (57%)
• Gaps: 174/1214 - (14%)

  Fly    42 ENVENGPTEYAENLVKVQMISRNLHAQLFPQAPRSISEQQVASAKVYKDELRRHGVDIESSAPVS 106
            |.:|...::...|.:.:||:|:.||||:|.......:|:.:..:   .:.|:.|.:..:.::.|.
 Frog    34 ETLETEMSQRRMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRS---INHLKSHELWGQETSTVP 95

  Fly   107 DVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTA 171
            |::|:||.|.|.:|||||..:|::|..||.|....|:.| |||..|:.||:.:|||.|     ||
 Frog    96 DIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLLNC-QLPTMPQTWAWQSGWTRY-----TA 154

  Fly   172 TP----VDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLSVEKLEPLDVDT 232
            |.    ||.|.||.||||||||||||..|.||.|||.:.||||.|.:|.:.|.:..|
 Frog   155 TGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSK-------- 211

  Fly   233 DSERPHYTTDELIPLGTT-----------GPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSL 286
                 ..:..:||||.|:           ...||||||:|:|||.:|||||.:.:..||:||||:
 Frog   212 -----ELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSM 271

  Fly   287 HMCVSGVTSYQRAMLKSKKEPAAEDL----------------------GWLEQSSLNSLVEVHRL 329
            ||.:||:|.:||.:..:.|....:.|                      .|:..||:|:|.:||.|
 Frog   272 HMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSKFDGSPISSWDWVNISSINNLADVHAL 336

  Fly   330 YCGGDTLSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGM 394
            |.||..|.||.|.:||:|::..:|..||.|..|||.||:|||.|.:..:||:.||.|||.:|:||
 Frog   337 YVGGPPLEKEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGM 401

  Fly   395 LEMGSAYLPVNSNWERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQNLWLWDEDWSV 459
            ||||.:|||||.|||||:.|||.:||:|..|.|..|...|.:||.||.:|.|:::.||||.:|.:
 Frog   402 LEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEWDI 466

  Fly   460 QELKLKQ---PPKRKPLPTVE-----------LKDSGNTPEERRLQAKFQHLYDQQ------ALL 504
            ||.|.|:   ..|:|.|...:           .:|:|...||...:.....:|.:.      .||
 Frog   467 QEFKQKKTKISKKQKRLKEAQESVGNKFIEDLNEDTGPPSEEEESRPSLAKIYLEDLKLKTLPLL 531

  Fly   505 PARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLH 569
            |.|...|||:|.||||||.|         |||.:  |.||.|.||..|::.|||:.|.|:|:|||
 Frog   532 PKRSQHLPGHPGWYRKLCPK---------LEDPD--WLPGPSLISLQMRLTPKLMRLTWDGFPLH 585

  Fly   570 YEREQGWGFLVPFRSDSEGVDRLPMEQLLAHCP---VPE-FARLSASKAESDMAFDMLPGQVEQH 630
            |..:.|||:|||.:.|:. ::....|.:|  ||   :.| |:..|.:||:.        .:|.:|
 Frog   586 YSEKHGWGYLVPGKKDNI-LNNEQEETIL--CPYRAIEEIFSEYSKNKAKD--------RRVSEH 639

  Fly   631 LGKREHY------------KKLSQKQQRLETQYQGSGVW-------------------------- 657
            ....|.:            ::||:.:..|..:...:|..
 Frog   640 SSLHEDFILTDDSSMWQKVEQLSRMEMDLSAEVPSTGTMKKRNNKPEPPAEPEFCSLPDYHHGNS 704

  Fly   658 -CNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVL--SSGDPSCQAAARVIDIARMMS 719
             |:.|....|:|.|||||:|.:..||:|.:||||.|..:..|  |.||.|   |.|.::|.:|:|
 Frog   705 PCSDVNVSGCWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSS---ATRALEINKMIS 766

  Fly   720 YWRNNRDRIMGQMVVWLDSQQLPNEFT--GEKCQPIAYGAICPQVVACGTLTRRAMEPTWMTASN 782
            :|||...||..|||||:...:||...|  .|..:...||.|.|.||:.||:||||:||||:||||
 Frog   767 FWRNAHKRISSQMVVWMKKGELPRTITRDPEYDEENKYGCILPLVVSAGTITRRAVEPTWLTASN 831

  Fly   783 SRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGS 847
            :|.||:||||::|||.||||.::||||||||||||::||:|:..|.||.|..|||||.|.||.|:
 Frog   832 ARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGT 896

  Fly   848 DMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRV 912
            |:||.||..|||||:||||.||.|||||||.|||.||.|||...:..:|..||.:|:::|||.|.
 Frog   897 DLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRR 961

  Fly   913 YRLREE---FHDEL-------EDRAYSSYEASRL---AIQRNRTLAEVFHRPNWQGGTESAMFNR 964
            |.|.:|   ..:||       |:.:.|..:..::   |..::|....:..|..|.|||||.|||:
 Frog   962 YILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKSRRKWNLVSRRIWTGGTESQMFNK 1026

  Fly   965 LEEIATGSQPRTPFLGGRLSRALE--ADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLM 1027
            ||.||....|:||.||..:|||||  |..|     .|:.:||||||||.|||:||||||:|:||.
 Frog  1027 LETIAMSPSPKTPVLGCHISRALEPAAVKG-----EFITSRINWVVQSSAVDYLHLMLVAMKWLF 1086

  Fly  1028 GSH---VRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEV 1089
            .::   .|||:|.|||:||||:.:...:||||:.||||:||....||:|:||||.||||||:|::
 Frog  1087 EAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDI 1151

  Fly  1090 DTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGG 1133
            |..||||.||||.|||||.|:...|||..|::|.:.:.::...|
 Frog  1152 DKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKG 1195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tam	NP_476821.1	DNA_pol_A	398..>440	CDD:295402	23/41 (56%)
		TRH	<420..539	CDD:283171	47/138 (34%)
		DNA_pol_gammaA	705..1107	CDD:176478	223/421 (53%)
polg	XP_002932281.3	DNApol_Exo	95..388	CDD:407968	129/311 (41%)
		DNA_pol_A	405..>447	CDD:413410	23/41 (56%)
		DNA_pol_gammaA	752..1169	CDD:176478	225/424 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	400	1.000	Domainoid score	I726
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2016
Inparanoid	1	1.050	872	1.000	Inparanoid score	I407
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192641at33208
OrthoFinder	1	1.000	-	-		FOG0004939
OrthoInspector	1	1.000	-	-		oto102270
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R347
SonicParanoid	1	1.000	-	-		X3481
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.090