Protein Alignment b and SGPL1

DIOPT Version :9

• Sequence 1: NP_001246025.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_003892.2
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 568
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 96/452 - (21%)
• Similarity: 161/452 - (35%)
• Gaps: 101/452 - (22%)

  Fly    75 NNITSTKDDLSSFVASHPAAEFEGFIRACVD-EIIKLAVFQGTNRSSKVVEWHEPAELRQLFDFQ 138
            :.:..||||:|..::         |::  || |.:|....||.: ||.|:|..:.......|..:
Human    90 DKLNKTKDDISKNMS---------FLK--VDKEYVKALPSQGLS-SSAVLEKLKEYSSMDAFWQE 142

  Fly   139 LREQG---ESQDKLRELLRETIRFSVKTGHPYFINQLYSGVDPYALVGQWLTDALNPSVYTYEVA 200
            .|..|   ..::||.|||       ||....:                .| ::.|:|.::
Human   143 GRASGTVYSGEEKLTELL-------VKAYGDF----------------AW-SNPLHPDIF----- 178

  Fly   201 PLFTLMEEQVLAEMRRIV-GFPNGGQGD-GIFCPGGSIANGYAISCARYRHSPESKKNGLFNAKP 263
            |....:|    ||:.||. ...|||... |....||:  ....::|..||.....|     ..|.
Human   179 PGLRKIE----AEIVRIACSLFNGGPDSCGCVTSGGT--ESILMACKAYRDLAFEK-----GIKT 232

  Fly   264 LIIFTSEDAHYSVEKLAMFMGFGSDHVRKIATNEVGKMRLSDLEKQVKLCLENGWQPLMVSATAG 328
            ..|...:.||.:..|.|.:.|.      ||....:.||...|:....:....|   ..|:..:..
Human   233 PEIVAPQSAHAAFNKAASYFGM------KIVRVPLTKMMEVDVRAMRRAISRN---TAMLVCSTP 288

  Fly   329 TTVLGAFDDLAGISEVCKKYNMWMHVDAAWGG---------GALMSKKYRHLLNGIERADSVTWN 384
            ....|..|.:..::::..||.:.:||||..||         |..:...:...:.|:   .|::.:
Human   289 QFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGV---TSISAD 350

  Fly   385 PHKLLAASQQCSTFLTRHQQVLAQCHSTNATYLFQKDKFYDTSFDTG---DKHIQCGRRADV-FK 445
            .||...|.:..|..|...::.        ..|.|    |.||.:..|   ...|...|...: ..
Human   351 THKYGYAPKGSSLVLYSDKKY--------RNYQF----FVDTDWQGGIYASPTIAGSRPGGISAA 403

  Fly   446 FWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELVLESPECTNISFWYVPPGLREME 507
            .|......|..|.....:::.:.|.|..:::....|. .|..:|:.:.|:.     |.|:.:
Human   404 CWAALMHFGENGYVEATKQIIKTARFLKSELENIKGI-FVFGNPQLSVIAL-----GSRDFD 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	78/388 (20%)
SGPL1	NP_003892.2	DOPA_deC_like	144..507	CDD:99743	79/386 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900