Protein Alignment b and GAD1

DIOPT Version :9

• Sequence 1: NP_001246025.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_013976.1
• Gene: GAD1 / 855291
• SGDID: S000004862
• Length: 585
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 104/567 - (18%)
• Similarity: 188/567 - (33%)
• Gaps: 167/567 - (29%)

  Fly   117 NRSSKVVEWHEPAELRQLFDFQLREQGESQDKLRELLRETI------RFSV-KTGHPYFINQLYS 174
            |.:.|||  |:.|.|:.|.:...:...:|..:....:|:|.      ::|| |.|.|..::
Yeast    14 NIAGKVV--HDLAGLQLLSNDVQKSAVQSGHQGSNNMRDTSSQGMANKYSVPKKGLPADLS---- 72

  Fly   175 GVDPYALVGQWLTDALNPSVYTYEVAPLFT------LMEE-----------------------QV 210
                |.|:...||...||.:........||      |::|                       .:
Yeast    73 ----YQLIHNELTLDGNPHLNLASFVNTFTTDQARKLIDENLTKNLADNDEYPQLIELTQRCISM 133

  Fly   211 LAEM------RRIVGFPNGGQGDGIFCPGGSIANGYAISCARYRHSPESKKNGLFNAKPLIIFTS 269
            ||::      ...:|....|..:.|...|.::..       |:.|  ..|..|...:||.||.:|
Yeast   134 LAQLWHANPDEEPIGCATTGSSEAIMLGGLAMKK-------RWEH--RMKNAGKDASKPNIIMSS 189

  Fly   270 E--------DAHYSVEKLAMFMGFGSDHVRK-------IATNEVGKMRLSDLEKQVKLCLENGWQ 319
            .        ..::.||...:.:...|.|:..       :..|.:|             |.
Yeast   190 ACQVALEKFTRYFEVECRLVPVSHRSHHMLDPESLWDYVDENTIG-------------CF----- 236

  Fly   320 PLMVSATAGTTVLGAFDDLAGISEVCK----KYNMW------MHVDAAWGGGAL-MSKKYRHL-L 372
                 ...|||..|..:::..:::|..    |:..|      :|.|.|.||..: ...:..|: .
Yeast   237 -----VILGTTYTGHLENVEKVADVLSQIEAKHPDWSNTDIPIHADGASGGFIIPFGFEKEHMKA 296

  Fly   373 NGIE-------RADSVTWNPHKLLAASQQCSTFLTRHQQVLAQCHSTNATYLFQKDKFYDTSFDT 430
            .|:|       |..|:..:.||....:......|.|.:.:||........||...::.:..:|..
Yeast   297 YGMERWGFNHPRVVSMNTSGHKFGLTTPGLGWVLWRDESLLADELRFKLKYLGGVEETFGLNFSR 361

  Fly   431 GDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELVLES--PECTN 493
            ..        ..|...:|.:.:.|..|.....:....:|..|:        |||:..|  |.|..
Yeast   362 PG--------FQVVHQYFNFVSLGHSGYRTQFQNSLFVARAFS--------FELLNSSKLPGCFE 410

  Fly   494 I------------------SFWYVP----PG--LREMERNREFYDRLHKVAPKVKEGMIKKGSMM 534
            |                  .:|..|    ||  |...:.:::|::...:|...:...:::....:
Yeast   411 IVSSIHESIENDSAPKSVKDYWEHPQAYKPGVPLVAFKLSKKFHEEYPEVPQAILSSLLRGRGWI 475

  Fly   535 ITYQPLRQLPN------FFRLVLQNSCLEESDMVYFLDEIESLAQNL 575
            |...||.:..:      ..|:|.::....:...:..:| |||:...|
Yeast   476 IPNYPLPKATDGSDEKEVLRVVFRSEMKLDLAQLLIVD-IESILTKL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	83/466 (18%)
GAD1	NP_013976.1	Glu-decarb-GAD	41..522	CDD:130848	95/538 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900