DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment b and Gadl1

DIOPT Version :9

Sequence 1:	NP_001246025.1	Gene:	b / 34791	FlyBaseID:	FBgn0000153	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001382689.1	Gene:	Gadl1 / 73748	MGIID:	1920998	Length:	522	Species:	Mus musculus

Alignment Length:	480	Identity:	247/480 - (51%)
Similarity:	338/480 - (70%)	Gaps:	5/480 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EGFIRACVDEIIKLAVFQGTNRSSKVVEWHEPAELRQLFDFQLREQGESQDKLRELLRETIRFSV 161
            |.|:......|::..|.:.|:.:.||.||..|.:||||.|.::|:.|||||||.:|.::.|.|||
Mouse    47 EKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSV 111

  Fly   162 KTGHPYFINQLYSGVDPYALVGQWLTDALNPSVYTYEVAPLFTLMEEQVLAEMRRIVGFPNGGQG 226
            ||.||.|.||||:|:|.|:|..:.:|:|||||:|||||:|:|.|:||.||.:|...||:.   :|
Mouse   112 KTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWK---EG 173

  Fly   227 DGIFCPGGSIANGYAISCARYRHSPESKKNGLFNAKPLIIFTSEDAHYSVEKLAMFMGFGSDHVR 291
            ||||.||||::|..|::.|||||.|:.|:.||.....||:|||.:.|||::|.|.|:|.|:.:|.
Mouse   174 DGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVY 238

  Fly   292 KIATNEVGKMRLSDLEKQVKLCLENGWQPLMVSATAGTTVLGAFDDLAGISEVCKKYNMWMHVDA 356
            .:.|:..|||...|||||:....:.|..|.:|.||:|||||||||.|..|:|||:::.:|:||||
Mouse   239 FVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDA 303

  Fly   357 AWGGGALMSKKYRHLLNGIERADSVTWNPHKLLAASQQCSTFLTRHQ-QVLAQCHSTNATYLFQK 420
            :|||.||:|:|:|.||:||.|||||.|||||:|.|..|||..|.:.: .:|.:|:|..||||||:
Mouse   304 SWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATYLFQQ 368

  Fly   421 DKFYDTSFDTGDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELV 485
            |||||.|:|||||.|||.||.|.||||..|||.||.|||..|.:.|.::.:...::::|.||:|:
Mouse   369 DKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLL 433

  Fly   486 LESPECTNISFWYVPPGLREMERNREFYDRLHKVAPKVKEGMIKKGSMMITYQPLRQLPNFFRLV 550
            :| ||.||:.|||:||.|||||...||:.:|..|||.:||.|:||||:|:.|||.|...||||.|
Mouse   434 ME-PEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQV 497

  Fly   551 LQNSCLEESDMVYFLDEIESLAQNL 575
            :.:..:...||.:.||||:||.:::
Mouse   498 VISPQVSREDMDFLLDEIDSLGRDM 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	199/371 (54%)
Gadl1	NP_001382689.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	426	1.000	Domainoid score	I611
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H45812
Inparanoid	1	1.050	515	1.000	Inparanoid score	I1283
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	1	1.000	-	-		otm44124
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45677
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	11.030