DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment b and Csad

DIOPT Version :9

Sequence 1:	NP_001246025.1	Gene:	b / 34791	FlyBaseID:	FBgn0000153	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_068518.1	Gene:	Csad / 60356	RGDID:	621030	Length:	493	Species:	Rattus norvegicus

Alignment Length:	480	Identity:	247/480 - (51%)
Similarity:	342/480 - (71%)	Gaps:	5/480 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EGFIRACVDEIIKLAVFQGTNRSSKVVEWHEPAELRQLFDFQLREQGESQDKLRELLRETIRFSV 161
            |..:|.....::..|:.:|||.|.||.||.||.||:||.|.:|:.||||::::.|..|..|.:||
  Rat    18 EALLRDVFGIVVDEAIRKGTNASEKVCEWKEPEELKQLLDLELQSQGESRERILERCRAVIHYSV 82

  Fly   162 KTGHPYFINQLYSGVDPYALVGQWLTDALNPSVYTYEVAPLFTLMEEQVLAEMRRIVGFPNGGQG 226
            |||||.|.|||:||:||:||.|:.:|::||.|.||||:||:|.||||:||.::|.:||:   ..|
  Rat    83 KTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGW---NTG 144

  Fly   227 DGIFCPGGSIANGYAISCARYRHSPESKKNGLFNAKPLIIFTSEDAHYSVEKLAMFMGFGSDHVR 291
            ||:|||||||:|.|||:.||::..|:.|:.||....||.:|||::.|||:.|.|.|:|.|:|.||
  Rat   145 DGVFCPGGSISNMYAINLARFQRYPDCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVR 209

  Fly   292 KIATNEVGKMRLSDLEKQVKLCLENGWQPLMVSATAGTTVLGAFDDLAGISEVCKKYNMWMHVDA 356
            .:..:|.|||...|||:|:.|....|..|.:||||:|||||||||.|..|::||:::.:|:||||
  Rat   210 VVKADERGKMIPEDLERQISLAEAEGSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWLHVDA 274

  Fly   357 AWGGGALMSKKYRHLLNGIERADSVTWNPHKLLAASQQCSTFLTRH-QQVLAQCHSTNATYLFQK 420
            ||||..|:|:.:||||:||:|||||.|||||||||..|||..|.|. ..:|.:||.:.|:||||:
  Rat   275 AWGGSVLLSRTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQ 339

  Fly   421 DKFYDTSFDTGDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELV 485
            ||||:.:.|||||.:|||||.|..|.|.||||:|.||||..:::.|.:..:...::::|.|||||
  Rat   340 DKFYNVALDTGDKVVQCGRRVDCLKLWLMWKAQGGQGLEWRIDQAFALTRYLVEEIKKREGFELV 404

  Fly   486 LESPECTNISFWYVPPGLREMERNREFYDRLHKVAPKVKEGMIKKGSMMITYQPLRQLPNFFRLV 550
            :| ||..|:.||:|||.||..:.:.::..||.:|||.:||.|:|||:|||.|||.....||||:|
  Rat   405 ME-PEFVNVCFWFVPPSLRGKKESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTRANFFRMV 468

  Fly   551 LQNSCLEESDMVYFLDEIESLAQNL 575
            :.|..|.::|:.:.|.|:|.|.|:|
  Rat   469 VANPILVQADIDFLLGELERLGQDL 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	199/371 (54%)
Csad	NP_068518.1	DOPA_deC_like	89..489	CDD:99743	211/403 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354455
Domainoid	1	1.000	427	1.000	Domainoid score	I582
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	519	1.000	Inparanoid score	I1229
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	1	1.000	-	-		oto98421
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45677
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X464
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.960