Protein Alignment b and gad2

DIOPT Version :9

• Sequence 1: NP_001246025.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001017708.2
• Gene: gad2 / 550403
• ZFINID: ZDB-GENE-030909-9
• Length: 583
• Species: Danio rerio
• Alignment Length: 544
• Identity: 231/544 - (42%)
• Similarity: 343/544 - (63%)
• Gaps: 21/544 - (3%)

  Fly    36 ATAALVASTSSPADSTSTVAFEQASKMLANAANNNNNNNNNITSTKDDLSS---FVASHPAAEFE 97
            |.|.:.|...|.|:|...               |...|.:..|:...||.|   ..|....|:..
Zfish    57 AQAPVKAEDESTAESCGC---------------NKPCNCSKATACFSDLYSTDLLPALDGDAKTM 106

  Fly    98 GFIRACVDEIIKLAVFQGTNRSSKVVEWHEPAELRQLFDFQLREQGESQDKLRELLRETIRFSVK 162
            .|::..|| |:...:.:..:||:||:::|.|.||.|..:::|.::.|:.|.:....|.|:::::|
Zfish   107 NFLQEVVD-ILLAYIVESFDRSTKVIDFHYPNELLQRNNWELSDEPETLDDILISCRATLKYAIK 170

  Fly   163 TGHPYFINQLYSGVDPYALVGQWLTDALNPSVYTYEVAPLFTLMEEQVLAEMRRIVGFPNGGQGD 227
            |.||.:.|||.:|:|...|...|||...|.:::||||||:|.|:|...|.:||.|:|:.: |.||
Zfish   171 TAHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEVAPVFVLLEYVTLKKMREIIGWQD-GHGD 234

  Fly   228 GIFCPGGSIANGYAISCARYRHSPESKKNGLFNAKPLIIFTSEDAHYSVEKLAMFMGFGSDHVRK 292
            |||.|||:|:|.||:..|||:..||.|:.|:.:...|:.||||.:|:|::|.|..:|.|::.|..
Zfish   235 GIFSPGGAISNMYAMLLARYKMFPEVKEKGMSSVPRLVAFTSEHSHFSIKKGAAALGIGTESVIC 299

  Fly   293 IATNEVGKMRLSDLEKQVKLCLENGWQPLMVSATAGTTVLGAFDDLAGISEVCKKYNMWMHVDAA 357
            |..:|.|||..||||:::....:.|:.|..|||||||||.||||.|..|:::|||:::|||||.|
Zfish   300 IKADERGKMIPSDLERRIIEAKQKGYVPFFVSATAGTTVYGAFDPLIAIADICKKHDVWMHVDGA 364

  Fly   358 WGGGALMSKKYRHLLNGIERADSVTWNPHKLLAASQQCSTFLTRHQQVLAQCHSTNATYLFQKDK 422
            |||..|||:|:|..|||:|||:|:||||||::|...|||..|.|.:.::..|:...|.||||:||
Zfish   365 WGGSLLMSRKHRWKLNGVERANSMTWNPHKMMAVPLQCSALLVREEGLMQSCNQMQACYLFQQDK 429

  Fly   423 FYDTSFDTGDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELVLE 487
            .||..:|||||.:||||..|:||.|.||:||||.|.||.::|...::|:...|:::|.|:::|.:
Zfish   430 HYDLQYDTGDKALQCGRHVDIFKLWLMWRAKGTIGFEAQIDKCLELSEYLYNKIKDREGYQMVFD 494

  Fly   488 -SPECTNISFWYVPPGLREMERNREFYDRLHKVAPKVKEGMIKKGSMMITYQPLRQLPNFFRLVL 551
             .|:.||:.|||:|||:|.:|...|...|||||||.:|..|::.|:.|::|||.....||||:|:
Zfish   495 GKPQHTNVCFWYLPPGVRYLEDKVERMKRLHKVAPVIKARMMEYGTTMVSYQPQGDKVNFFRMVI 559

  Fly   552 QNSCLEESDMVYFLDEIESLAQNL 575
            .|......|:.:.::|||.|.|:|
Zfish   560 SNPAATFEDIDFLIEEIERLGQDL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	174/371 (47%)
gad2	NP_001017708.2	Pyridoxal_deC	136..506	CDD:278699	173/370 (47%)
		TIM_phosphate_binding	511..>561	CDD:304361	22/49 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920