DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment b and CG1486

DIOPT Version :9

Sequence 1:	NP_001246025.1	Gene:	b / 34791	FlyBaseID:	FBgn0000153	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_608450.1	Gene:	CG1486 / 33108	FlyBaseID:	FBgn0031174	Length:	852	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	76/381 - (19%)
Similarity:	134/381 - (35%)	Gaps:	109/381 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 AKPLIIFTSEDA-----HYSVEKLAMFMGFGSDHVRKIAT-NEVGKMRLSDLEKQVKLCLENGWQ 319
            |:| ..:.||:.     ||:..:|    |...:.::.|.. ::.|.|.::.|:||::..:.|...
  Fly   206 AQP-TFYISENTTPMRLHYACRQL----GIPLEAIKVIPEHSQSGTMDVTLLQKQIQQDVGNNRT 265

  Fly   320 PLMVSATAGTTVLGAFDDLAGISEVCKKYNMWMHVDAAWGGGALMSKKYRHLLNGIERADSVTWN 384
            ||:|.|..|.::.|..|:|..:.:|||.:|||:|.........:.::...|:   .|...|:..|
  Fly   266 PLLVVADIGASLCGYVDNLLRLRDVCKAHNMWLHASGHGLAALVCAQNQGHV---EEVLHSMALN 327

  Fly   385 PHKLLAASQQCSTFLTRHQQVLAQCHSTNATYLFQKDKFYDTSFDTGDKHIQCGRRADVFKFWFM 449
            ....|.........|.|..|       .:|...|:.|..             ..||.:....|..
  Fly   328 LGSWLGVPSLPIVLLHRPLQ-------NSALSAFESDPI-------------LSRRLNALSLWTS 372

  Fly   450 WKAKGTQGLEAHVEKVFRMAEF---FTAK------VRERPGFEL------VLESPECTNISFWYV 499
            .:|.|.:.:...:...|:....   ..:|      :...||.:.      |::||......|...
  Fly   373 LQALGRKAIAERLHVAFQTCSILFEIASKCEGIRVLSHTPGAQTGASLSDVIQSPFDVQALFDAA 437

  Fly   500 PP--------------------------------GLREMER--NREFYDRLHKVAPKVKEGMIKK 530
            .|                                ||:.:|:  |..::|||:....::.:
  Fly   438 APVVAYQFDGSTTIPLGGSGSSAAAAAAERETAEGLKPLEKINNASYFDRLNSWLGQILQ----- 497

  Fly   531 GSMMITYQPLRQLPNFFRLVLQN----SCLEESDMVYFLDE-------IESLAQNL 575
                      |..|||...|:::    ||:....:...|.|       :||.||:|
  Fly   498 ----------RDCPNFDFEVIEHPTHGSCIRYCPLELGLGEQPPSSENLESFAQSL 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	54/258 (21%)
CG1486	NP_608450.1	AAT_I	159..>384	CDD:302748	46/205 (22%)
CG1486	NP_608450.1	WWbp	<725..801	CDD:304964
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930