Protein Alignment b and hdl-1

DIOPT Version :9

• Sequence 1: NP_001246025.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_502265.2
• Gene: hdl-1 / 178129
• WormBaseID: WBGene00001839
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 655
• Identity: 137/655 - (20%)
• Similarity: 243/655 - (37%)
• Gaps: 142/655 - (21%)

  Fly    11 HFKESIFK--PYSTTSGDDLASVSPLTATAALVASTSSPADSTSTVAFEQASKMLANAANNNNNN 73
            :|.|:..:  |:.|...|.|   :|:..|         |..:      |:..||..|.:......
 Worm   232 YFSETKSRQAPFRTPEADYL---NPIIKT---------PPHN------ERVPKMKTNISKTRKKK 278

  Fly    74 NNNITSTKDDLSS---------------------------FVASHPAAEFE--GFIRACVDEIIK 109
            .....::||...|                           |.......||:  ..::..|| :..
 Worm   279 GKVSDASKDSRPSETKKETLMMPEIHHTKHFDSIGGEEQAFAKKEKVEEFKPTEAVKEEVD-VNG 342

  Fly   110 LAVFQGTNRSSKVVEW----------------HEPAELRQLFDFQLREQGESQDKLRELLRETIR 158
            ::..|..|.:.|||::                .:|..|:.|...:..::.|..|.:.|...:.|.
 Worm   343 MSRDQFRNAAKKVVDYLMKQDESIRAARCSPALKPGYLKALLPPKAPQKAEDIDDILEDYHKLIV 407

  Fly   159 FSVK-TGHPYFINQLYSGVDPY-----ALVGQWLTDA-----LNPSVYTYEVAPLFTLMEEQVLA 212
            ..:. :.||.| :..|...:.:     .|:|..:.||     .||::...||..:..|.|  ::|
 Worm   408 PGLSHSSHPNF-HSFYPAGNSFHCLLADLLGGHIGDAGFYWTSNPALTELEVLMMDWLGE--MMA 469

  Fly   213 EMRRIVGFPNGGQGDGIFCPGGSIANGYAISCA------RYRHSPESKKNGLFNAKPLIIFTSED 271
            ..:..:.||...:|.|......:.:|...:..|      |.:...:..::....|: |:.:||.|
 Worm   470 LPKEFLLFPEASRGGGCMQRSDTESNFLVLVAARTDMIRRMKQRDKRLRSSDILAR-LVAYTSSD 533

  Fly   272 AHYSVEKLAMFMGFGSDHVRKIATNEVGKMRLSDLEKQVKLCLENGWQPLMVSATAGTTVLGAFD 336
            |..|: |:.|........:|.:.|::...:|...|...:...:|.|..|..|.|..||:...:||
 Worm   534 ARRSI-KMKMAAEVAMVKMRVLPTDQNFILRGDTLHAAIMADIERGLIPFFVGANFGTSGPCSFD 597

  Fly   337 DLAGISEVCKKYNMWMHVDAAWGGGALMSKKYRHLLNGIERADSVTWNPHKLLAASQQCSTFLTR 401
            .|..:..||:::..|:|||||:.|.||:..:.|.|:.||:.|||....|.||:.|.........|
 Worm   598 HLHELGPVCREHGTWLHVDAAYAGTALICPEIRGLMRGIDWADSFCTTPSKLIIAVCDVCCLWVR 662

  Fly   402 HQQVLAQCHSTNATYLFQKDKFYDTSFDTGDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVF 466
            .:..|......|..         |..|    |.:...:|....|.|||.::.|.:.|:..:.:..
 Worm   663 DRHKLQHASLENHP---------DLPF----KGLPTSQRVGALKIWFMIRSFGVENLQNQIREHI 714

  Fly   467 RMAEFFTAKVRERPGFE-----------------------LVLESPECTNISFWYVPPGLREMER 508
            |:.:..|..:::...||                       |:....|..|:|       |.....
 Worm   715 RLGQVMTKILQKDLRFEVCNKVVMGLICFRAKSNDMFNKALLYRCNETGNVS-------LASCVL 772

  Fly   509 NREFYDRLHKVAPKVKEGMIKKGSMMI--TYQPLRQLPNFFRLVLQNSCLEESDMVYFLDE---I 568
            ..:|..|:...:||..|..:.....:|  .|..|:  |..:|:.:.|    ::::..|:.:   |
 Worm   773 QNKFVIRMCINSPKCSEEDLDSAYKLICNEYDILK--PFQYRIEVMN----QAELETFIRDPAKI 831

  Fly   569 ESLAQ 573
            .|.|:
 Worm   832 HSSAE 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_001246025.1	AAT_I	128..499	CDD:302748	95/410 (23%)
hdl-1	NP_502265.2	Pyridoxal_deC	377..746	CDD:278699	91/386 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900