Protein Alignment b and Tdc2

DIOPT Version :10

• Sequence 1: NP_476788.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_308519.3
• Gene: Tdc2 / 1269865
• VectorBaseID: AGAMI1_013508
• Length: 642
• Species: Anopheles gambiae
• Alignment Length: 497
• Identity: 128/497 - (25%)
• Similarity: 208/497 - (41%)
• Gaps: 82/497 - (16%)

  Fly   116 TNRSSKVVEWHEPAELRQLFDFQLREQGESQDKLRELLRETIRFSV-KTGHPYFINQLYSGVDPY 179
            |....:|....||..|:.....:..|:.|..:|:.:.:.:.|...| ...||.|.....||....
Mosquito    23 TLEQRRVTPCVEPGYLKHQLPDEAPEEPEPWEKIMQDVEDKIMPGVTHWQHPRFHAYFPSGNSFP 87

  Fly   180 ALVGQWLTDALNPSVYTYEVAPLFTLMEEQVLAEMRRIVGFPN-------GGQGDGIFCPGGS-- 235
            :::|..|:|.:....:::..:|..|.:|..||..:.:.:|.|:       |.:|.|:.....|
Mosquito    88 SILGDMLSDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPDSFLALKPGSRGGGVIQTSASEC 152

  Fly   236 ------IANGYAISCARYRHSPESKKNGLFNAKPLIIFTSEDAHYSVEKLAMFMGFGSDHVRKIA 294
                  .|...||...:.:| |..::..|.:  .|:.:.|::||..|||.||
Mosquito   153 VLVTMLAARAQAIKYLKQQH-PFVEEGHLLS--KLMAYCSKEAHSCVEKAAM------------- 201

  Fly   295 TNEVGKMRLSDLEKQVKLCL-------------ENGWQPLMVSATAGTTVLGAFDDLAGISEVCK 346
               :..::|..||...|.||             :.|..|..||.|.|||...||||||.|.|..:
Mosquito   202 ---ISFVKLRILEPDEKCCLRADTLIKAMEEDEQQGLIPFFVSTTLGTTGSCAFDDLAEIGEALQ 263

  Fly   347 KY-NMWMHVDAAWGGGALMSKKYRHLLNGIERADSVTWNPHKLLAASQQCSTFLTRHQQVLAQCH 410
            :: ::|:|||||:.|.|.:..:.::||.||:.|||...||:|.|..:..|||...|.:..|....
Mosquito   264 RFPSVWLHVDAAYAGNAFICPELKYLLKGIQYADSFNTNPNKWLLTNFDCSTLWVRDRIRLTSAL 328

  Fly   411 STNATYLFQKDKFYDTSFDTGDKHIQCGRRADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAK 475
            ..:..||  :..:.|::.|.....:...||....|.||:.::.|..||:|::.....:|:.|.|.
Mosquito   329 VVDPLYL--QHGYTDSAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQAYIRHHIELAKRFEAL 391

  Fly   476 VRERPGFELVLESPECTNISFWYVPPGLREMERNRE-------FYDRLHKVAPKVKEGMIKKGSM 533
            |.:...||:      |..:....|...|:..:|..|       ...:||.|...|.:..:.:
Mosquito   392 VLKDSRFEV------CNEVRLGLVCFRLKGTDRINEKLLSSINASGKLHMVPASVNDTYVIR--- 447

  Fly   534 MITYQPLRQLPNFFRLVLQNSCLEESDMVYFLDEIESLAQNL 575
                         |..|.||:.:|:.|  |..|.|...|..:
Mosquito   448 -------------FCAVAQNAKVEDID--YAWDVITDFASEI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_476788.1	GadA	127..573	CDD:439846	125/482 (26%)
Tdc2	XP_308519.3	Pyridoxal_deC	35..414	CDD:395219	108/405 (27%)