Protein Alignment b and gad1

DIOPT Version :10

• Sequence 1: NP_476788.1
• Gene: b / 34791
• FlyBaseID: FBgn0000153
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_004917766.1
• Gene: gad1 / 100496528
• XenbaseID: XB-GENE-1011699
• Length: 590
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 241/527 - (45%)
• Similarity: 346/527 - (65%)
• Gaps: 12/527 - (2%)

  Fly    58 QASKMLANAANNNNNNNNNITSTKDDLSSFVASH--PAAEFEGFIRACVDEIIKLA---VFQGTN 117
            ||||.|  ....|...::.....:.|.|:..|..  ||...|.|....:.|::.:.   |.:..:
 Frog    67 QASKNL--LVCENIEKDSQFRRAETDFSNLFARDLLPAKNGEEFTMQFLLEVVDILLNYVRKTFD 129

  Fly   118 RSSKVVEWHEPAELR---QLFDFQLREQGESQDKLRELLRETIRFSVKTGHPYFINQLYSGVDPY 179
            ||:||:::|.|.:|.   :.|:.:|.:..||.:::....|:|:::.|:||||.|.|||.:|:|..
 Frog   130 RSTKVLDFHHPHQLLEGIEGFNLELSDNPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDII 194

  Fly   180 ALVGQWLTDALNPSVYTYEVAPLFTLMEEQVLAEMRRIVGFPNGGQGDGIFCPGGSIANGYAISC 244
            .|.|:|||...|.:::|||:||:|.|||:..|.:||.|:|:.. ..|||||.|||:|:|.|:|..
 Frog   195 GLAGEWLTSTANTNMFTYEIAPVFVLMEQITLRKMREIIGWTE-KDGDGIFSPGGAISNMYSIMA 258

  Fly   245 ARYRHSPESKKNGLFNAKPLIIFTSEDAHYSVEKLAMFMGFGSDHVRKIATNEVGKMRLSDLEKQ 309
            |||::.||.|..|:.....|::||||.:|||::|....:||||::|..:.|||.||:..:|||.:
 Frog   259 ARYKYFPEVKTKGMAAVPRLVLFTSEHSHYSIKKTGAALGFGSENVIMVKTNERGKIIPADLEAK 323

  Fly   310 VKLCLENGWQPLMVSATAGTTVLGAFDDLAGISEVCKKYNMWMHVDAAWGGGALMSKKYRHLLNG 374
            :....:.|:.||.|:|||||||.||||.::.|:::|:|||:|:|||||||||.|||:::||.|:|
 Frog   324 ILEAKQKGYVPLYVNATAGTTVYGAFDPISEIADICEKYNLWLHVDAAWGGGLLMSRRHRHKLDG 388

  Fly   375 IERADSVTWNPHKLLAASQQCSTFLTRHQQVLAQCHSTNATYLFQKDKFYDTSFDTGDKHIQCGR 439
            ||||:||||||||::....|||..|.|.:.:|..|:...|.||||:||.||.|:|||||.|||||
 Frog   389 IERANSVTWNPHKMMGVLLQCSAILLREKGILQGCNQMCAGYLFQQDKQYDISYDTGDKAIQCGR 453

  Fly   440 RADVFKFWFMWKAKGTQGLEAHVEKVFRMAEFFTAKVRERPGFELVLES-PECTNISFWYVPPGL 503
            ..|:||||.|||||||.|.||.:.|...:||:..:|:..|.|||:|... ||.||:.|||:||.|
 Frog   454 HVDIFKFWLMWKAKGTVGFEAQINKCLELAEYLYSKIYNREGFEMVFNGVPEHTNVCFWYIPPSL 518

  Fly   504 REMERNREFYDRLHKVAPKVKEGMIKKGSMMITYQPLRQLPNFFRLVLQNSCLEESDMVYFLDEI 568
            |.|..|.|..::||:||||:|..|::.|:.|:.|||.....||||:|:.|....:||:.:.::||
 Frog   519 RGMPNNEEKQEKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATKSDIDFLVEEI 583

  Fly   569 ESLAQNL 575
            |.|.|.|
 Frog   584 ERLGQEL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
b	NP_476788.1	GadA	127..573	CDD:439846	219/449 (49%)
gad1	XP_004917766.1	Pyridoxal_deC	140..514	CDD:395219	186/374 (50%)