| Sequence 1: | NP_476597.2 | Gene: | Sos / 34790 | FlyBaseID: | FBgn0001965 | Length: | 1596 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_076111.2 | Gene: | Rgl3 / 71746 | MGIID: | 1918996 | Length: | 709 | Species: | Mus musculus |
| Alignment Length: | 674 | Identity: | 176/674 - (26%) |
|---|---|---|---|
| Similarity: | 258/674 - (38%) | Gaps: | 159/674 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 650 IERLTYHIYA-----DPTFVRTFLTTYRYFCSPQQLLQLLVERFNIPDPSLVYQDTGTAGAGGMG 709
Fly 710 GVGGDKEHKNSHREDWKRYRKEYVQPVQFRVLNVLRHWVDHHFYDFEKDPMLLEKLLN---FL-- 769
Fly 770 ---EHVNGKSMRKWVDSVLKIVQRKNEQEKSNKKIVYAYGHDPPPIEHHLSVPNDEIT------- 824
Fly 825 --------LLTLHPLELARQLTLLEFEMYKNVKPSELVGSPWTKKDKEVK---SPNLLKIMKHTT 878
Fly 879 NVTRWIEKSITEAENYEERLAIMQRA------IEVMMVMLELNNFNGILSIVAAMGTASVYRLRW 937
Fly 938 TFQGLPERYRKFLEECRELS------DDHLKK----YQER-----------LRSINPP-CVPFFG 980
Fly 981 RYLTNILHLEEGNPDLLANTELINFSKRRKVAEIIGEIQQYQN--QPYCLNEESTIRQFFEQLDP 1043
Fly 1044 FNGLSDKQMSDYLYNESLRIEP--RGCKTVPKFPRKWPHIPLKSPGIKPRRQNQTNSSSKLSNST 1106
Fly 1107 SSVAAAAAA--SSTATSIATASAPSLHASSIMDAPTAAAANAGSGTLAGEQSPQHNPHAFSVFAP 1169
Fly 1170 VIIPERNTSSWSGTPQHTRTDQNNGEVSVPAPHLPKKPGAHVWANNNS-------TLASASAMDV 1227
Fly 1228 VFSPALPEHLPPQSLPDSNPFASD 1251 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sos | NP_476597.2 | Histone | 90..216 | CDD:278551 | |
| H2A | 155..>196 | CDD:305064 | |||
| RhoGEF | 249..432 | CDD:238091 | |||
| PH_SOS | 476..586 | CDD:269963 | |||
| PH | 482..587 | CDD:278594 | |||
| RasGEFN | 637..791 | CDD:214571 | 37/153 (24%) | ||
| RasGEF | 825..1062 | CDD:238087 | 82/269 (30%) | ||
| Rgl3 | NP_076111.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..55 | ||
| REM | 73..199 | CDD:100121 | 37/151 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 203..225 | 7/27 (26%) | |||
| RasGEF | 244..503 | CDD:214539 | 84/273 (31%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 395..416 | 4/20 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 502..604 | 28/122 (23%) | |||
| Interaction with HRAS, MRAS and RIT1. /evidence=ECO:0000269|PubMed:10869344, ECO:0000269|PubMed:11313946 | 611..706 | 16/65 (25%) | |||
| RalGDS_RA | 612..697 | CDD:176351 | 16/64 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||