| Sequence 1: | NP_476597.2 | Gene: | Sos / 34790 | FlyBaseID: | FBgn0001965 | Length: | 1596 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_689876.2 | Gene: | RALGPS2 / 55103 | HGNCID: | 30279 | Length: | 583 | Species: | Homo sapiens |
| Alignment Length: | 514 | Identity: | 107/514 - (20%) |
|---|---|---|---|
| Similarity: | 196/514 - (38%) | Gaps: | 136/514 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 825 LLTLHPLELARQLTLLEFEMYKNVKPSELVGSPWTKKDKEVKSPNLLKIMKHTTNVTRWIEKSIT 889
Fly 890 EAENYEERLAIMQRAIEVMMVMLELNNFNGILSIVAAMGTASVYRLRWTFQGLPERYRKFLEECR 954
Fly 955 EL--SDDHLKKYQERLRSIN-PPCVPFFGRYLTNILHLEEGNP---DLLANTELINFSKRRKVAE 1013
Fly 1014 IIGEIQQY---------QNQPYCLNEESTIRQFFEQLDPFNGLSDKQMSDYLYNESLRIEPRGCK 1069
Fly 1070 TVPKFPRKWPHIPLKSPGIKPRRQNQTNSSSKLSNSTSSVAAAAAASSTATSIATASAPSLHASS 1134
Fly 1135 IMDAPTAAAAN-AGSGTLAGEQSPQHN---PHAFSVFAPV---IIPERNTSSWSGT------PQH 1186
Fly 1187 TRTDQNNGEVSVPAPHLPKKPGAHVWANNNSTLASASAMDVVFSPALPEHLPPQSLPDSNPFASD 1251
Fly 1252 TEAPPSPLPKLVVSPRHETG-----NRSPFHGRMQNSPT--------HSTASTVTLTGM 1297 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sos | NP_476597.2 | Histone | 90..216 | CDD:278551 | |
| H2A | 155..>196 | CDD:305064 | |||
| RhoGEF | 249..432 | CDD:238091 | |||
| PH_SOS | 476..586 | CDD:269963 | |||
| PH | 482..587 | CDD:278594 | |||
| RasGEFN | 637..791 | CDD:214571 | |||
| RasGEF | 825..1062 | CDD:238087 | 62/251 (25%) | ||
| RALGPS2 | NP_689876.2 | RasGEF | 45..286 | CDD:214539 | 64/254 (25%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 283..314 | 9/81 (11%) | |||
| PXXP | 324..327 | 0/2 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 372..406 | 12/59 (20%) | |||
| Required for stimulation of nucleotide exchange by RALA. /evidence=ECO:0000250 | 459..583 | 2/5 (40%) | |||
| PH_RalGPS1_2 | 459..574 | CDD:270120 | 2/5 (40%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3417 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||