DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and Adarb2

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_017171136.1	Gene:	Adarb2 / 94191	MGIID:	2151118	Length:	747	Species:	Mus musculus

Alignment Length:	231	Identity:	76/231 - (32%)
Similarity:	114/231 - (49%)	Gaps:	32/231 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAELCLKKFESLPKTGKPTANQWTILAGIV-EFNRNTEACQLVSLGCGTKCIGESKLCPNGLILN 75
            :::|..:||..|.........:...||||| ....:|:..|::.|..|||||....:...||::|
Mouse   371 VSQLVTQKFRELTVGLTSVYARHKTLAGIVMTKGLDTKQAQVIVLSSGTKCISGEHISDQGLVVN 435

  Fly    76 DSHAEVLARRGFLRFLYQELK---------QDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGDAC 131
            |.|||::|||.||.|||.:|:         .:|..........|.:.|::.||...:.:|||||.
Mouse   436 DCHAEIVARRAFLHFLYSQLELHLSKHQEDPERSIFIRLKEGGYRLRENILFHLYVSTSPCGDAR 500

  Fly   132 I---------LEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPG--RGER 185
            :         |...:...|..|..|         ..|:.|.....| ::.|.|::|..|  .||:
Mouse   501 VNSPYEITTDLNSSKHIVRKFRGHL---------RTKIESGEGTVP-VRGPSAVQTWDGILLGEQ 555

  Fly   186 TLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSL 221
            .::|||:||||.|||:|:|||||...| :|:|..|:
Mouse   556 LITMSCTDKIASWNVLGLQGALLCHFI-EPVYLHSI 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	76/231 (33%)
Adarb2	XP_017171136.1	DSRM_RED2_rpt1	122..195	CDD:380725
		DSRM_SF	276..349	CDD:381777
		ADEAMc	366..739	CDD:214718	76/231 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2777
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2305
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950